EIF4A2 and SSX2IP

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EIF4A2	SSX2IP
Gene Name		eukaryotic translation initiation factor 4A2	synovial sarcoma, X breakpoint 2 interacting protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 4F Complex Perinuclear Region Of Cytoplasm	Nucleus Cell-cell Adherens Junction Cell Leading Edge Centriolar Satellite Ciliary Basal Body Protein Complex
	Molecular Function	Translation Initiation Factor Activity Helicase Activity Protein Binding ATP Binding ATPase Activity Poly(A) RNA Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Translation Translational Initiation Regulation Of Translational Initiation Gene Expression Viral Process Cytokine-mediated Signaling Pathway Cellular Protein Metabolic Process Negative Regulation Of RNA-directed RNA Polymerase Activity	Cell Adhesion Regulation Of Rac Protein Signal Transduction Intraciliary Transport Involved In Cilium Morphogenesis Cilium Assembly Centrosome Organization Regulation Of Cell Motility
Pathways		Translation initiation complex formation Translation Deadenylation of mRNA ISG15 antiviral mechanism Interferon Signaling Cytokine Signaling in Immune system L13a-mediated translational silencing of Ceruloplasmin expression Antiviral mechanism by IFN-stimulated genes Deadenylation-dependent mRNA decay Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Cap-dependent Translation Initiation
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: BRCA1 CLNS1A DPPA4 ECT2 EIF4G1 EIF4G2 IPO11 MDFI NEK2 PDCD4 PFDN1 PIH1D2 SLC16A9 SSX2IP TK1 TRIM36 TRIM39	89 interactors: ABLIM3 ACTN1 ACTN2 AEN AP1M1 ARNT2 BEX2 BRCA1 BYSL C11orf54 C14orf105 C19orf66 C20orf195 CARD9 CCHCR1 CCNH CDC23 CDC42 CDCA7L CEP55 CHCHD3 DAXX DRG1 EHHADH EIF4A2 FAM124B FAM161A FAM214A FAM64A FANCL FBF1 FRMD6 GEM GOLGA8F IKBKG INO80B KAT5 KDM1A KIF9 KLHL42 KRT15 KRT31 KRT40 KRTAP10-7 LATS1 LMO2 MFAP1 MLLT4 MORN4 MOS MRPL53 NAA10 NDN NOL12 PHC2 PKN1 POLL PRKAA1 PRMT6 PRPF31 PSMA1 SCNM1 SSX2 SSX3 SYT17 TBP TEAD4 TFIP11 TOP3B TP53BP2 TRIM37 TRIM42 TRIM54 TTC23 WDR5 XIAP YWHAQ YWHAZ ZBTB24 ZGPAT ZMAT2 ZNF124 ZNF250 ZNF3 ZNF417 ZNF587 ZNF792 ZRSR2 ZSCAN12
Entrez ID		1974	117178
HPRD ID		03062	10566
Ensembl ID		ENSG00000156976	ENSG00000117155
Uniprot IDs		Q14240 Q9NZE6	B7ZB07 Q9Y2D8
PDB IDs		3BOR
Enriched GO Terms of Interacting Partners?		Regulation Of Cell Cycle Centrosome Organization Microtubule Organizing Center Organization Regulation Of Attachment Of Spindle Microtubules To Kinetochore Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Microtubule-based Process Regulation Of Protein Metabolic Process Negative Regulation Of DNA Binding Cell Death Death Regulation Of Centrosome Cycle Centrosome Cycle Positive Regulation Of Histone H4-K20 Methylation Negative Regulation Of Centriole-centriole Cohesion Positive Regulation Of Histone H4-K16 Acetylation Fetal Process Involved In Parturition Regulation Of Translational Initiation Regulation Of JUN Kinase Activity Skeletal Muscle Cell Proliferation Positive Regulation Of Histone H3-K9 Acetylation Regulation Of Chromosome Segregation Cell Cycle Regulation Of DNA Binding Embryo Development Ending In Birth Or Egg Hatching Negative Regulation Of Binding Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Regulation Of Centriole-centriole Cohesion Microtubule Cytoskeleton Organization Negative Regulation Of Cell Cycle Apoptotic Process Cellular Response To Indole-3-methanol Regulation Of Mitotic Centrosome Separation Programmed Cell Death Regulation Of Cell Cycle Process Developmental Process Ribosomal Protein Import Into Nucleus Intraciliary Transport Involved In Cilium Morphogenesis Negative Regulation Of Centriole Replication Response To Cortisol Thymidine Metabolic Process Cell Cycle Process Regulation Of Cytoskeleton Organization Response To Ionizing Radiation Dosage Compensation By Inactivation Of X Chromosome Deoxyribonucleoside Monophosphate Biosynthetic Process Protein K6-linked Ubiquitination Regulation Of JNK Cascade Negative Regulation Of Cytoskeleton Organization	Gene Expression RNA Metabolic Process Transcription, DNA-templated Nucleobase-containing Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Organelle Organization Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Chromosome Organization Biosynthetic Process Regulation Of Metabolic Process Signal Transduction By P53 Class Mediator Cellular Process Cellular Metabolic Process Cellular Response To DNA Damage Stimulus Intracellular Signal Transduction Positive Regulation Of Protein Modification Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Histone H3-K4 Methylation Regulation Of Apoptotic Process Regulation Of Cellular Process Viral Process Cellular Response To Stress Cell Cycle Regulation Of Cell Death Chromatin Organization Cell Cycle Process Negative Regulation Of Cell Cycle Activation Of MAPK Activity Response To Ionizing Radiation Chromatin Modification Apoptotic Signaling Pathway Regulation Of Organelle Organization DNA Damage Response, Signal Transduction By P53 Class Mediator Establishment Of Golgi Localization Negative Regulation Of Centriole Replication Positive Regulation Of Cellular Protein Metabolic Process Adherens Junction Organization
Tagcloud ?		4f adult biogenesis confer deprivation differed differs eif4f eif4g1 fetal gestation helicase hepatocyte insensitive liver nutrient oligopyrimidine preinitiation rapamycin refeeding ribosome sensing top tracts translation weights went
Tagcloud (Difference) ?		4f adult biogenesis confer deprivation differed differs eif4f eif4g1 fetal gestation helicase hepatocyte insensitive liver nutrient oligopyrimidine preinitiation rapamycin refeeding ribosome sensing top tracts translation weights went
Tagcloud (Intersection) ?