HERC5 and CCND1

  • Number of citations of the paper that reports this interaction (PMID 10581175)
  • 11
  • Data Source:
  • HPRD (in vivo)

HERC5

CCND1

Gene Name HECT and RLD domain containing E3 ubiquitin protein ligase 5 cyclin D1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Pulmonary function decline ( 22424883)
Protein-Protein Interactions 10 interactors: CCNA2 CCNB1 CCND1 CCNE1 CDKN1A ERCC2 NME2 PITX2 STK38 UBE2D1 60 interactors: AKAP8 AR ARID4A ATF2 BRCA1 BRINP1 BTRC CALM1 CAMK1 CCNDBP1 CDK4 CDK6 CDKN1A CDKN1B CDKN1C CDKN2A CRYAB CTNNB1 CUL3 DMTF1 EP300 ESR1 FBXO31 FBXO4 GSK3B HDAC3 HERC5 IFI27 INSM1 KAT2B LPL MAPK11 MCM10 MCM7 MYBL2 NCOA1 NCOA3 NPDC1 ORC4 PCNA POLR1B PRKACA RABEP1 RB1 RBL1 RBL2 RBX1 RFC1 RUNX1 SP1 STAT3 TAF1 THRA THRB TP73 TSC2 UBTF UHRF2 USP2 XPO1
Entrez ID 51191 595
HPRD ID 10502 01346
Ensembl ID ENSG00000138646 ENSG00000110092
Uniprot IDs B4DXV3 E9PBL0 Q9UII4 P24385 Q6FI00
PDB IDs 2W96 2W99 2W9F 2W9Z
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accumulation  alternative  attractive  deletion  drugs  enhancing  inactivation  involving  isg15  isgylation  multistep  native  oncogene  oncogenes  p53  promoting  propose  regulate  src  stability  suppressing  suppressor  suppressors  transformation  transformed  tumorigenesis  turn  tyr126  tyr220 
11q13  4nqo  7f4  amplicon  amplification  amplified  cavity  chr  distal  example  fgf3  fgf4  heterozygosity  hras1  inbred  inconsistently  involving  loh  murine  neck  nitroquinoline  portion  predispose  scc  strikingly  syntenic  telomeric  thirds  twofold 
Tagcloud (Difference) ?
accumulation  alternative  attractive  deletion  drugs  enhancing  inactivation  isg15  isgylation  multistep  native  oncogene  oncogenes  p53  promoting  propose  regulate  src  stability  suppressing  suppressor  suppressors  transformation  transformed  tumorigenesis  turn  tyr126  tyr220 
11q13  4nqo  7f4  amplicon  amplification  amplified  cavity  chr  distal  example  fgf3  fgf4  heterozygosity  hras1  inbred  inconsistently  loh  murine  neck  nitroquinoline  portion  predispose  scc  strikingly  syntenic  telomeric  thirds  twofold 
Tagcloud (Intersection) ?
involving