HERC5 and ERCC2

  • Number of citations of the paper that reports this interaction (PMID 16884686)
  • 17

HERC5

ERCC2

Gene Name HECT and RLD domain containing E3 ubiquitin protein ligase 5 excision repair cross-complementation group 2
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Pulmonary function decline ( 22424883)
  • Lung Cancer (DNA repair capacity) ( 23108145)
Protein-Protein Interactions 10 interactors: CCNA2 CCNB1 CCND1 CCNE1 CDKN1A ERCC2 NME2 PITX2 STK38 UBE2D1 14 interactors: AR CDK1 CDK7 ERCC3 ERCC5 GTF2H1 GTF2H2 GTF2H2C_2 GTF2H3 HERC5 RAD51 RAD52 TP53 TRIM25
Entrez ID 51191 2068
HPRD ID 10502 00530
Ensembl ID ENSG00000138646 ENSG00000104884
Uniprot IDs B4DXV3 E9PBL0 Q9UII4 E7EVE9 P18074
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
accumulation  alternative  attractive  deletion  drugs  enhancing  inactivation  involving  isg15  isgylation  multistep  native  oncogene  oncogenes  p53  promoting  propose  regulate  src  stability  suppressing  suppressor  suppressors  transformation  transformed  tumorigenesis  turn  tyr126  tyr220 
bcnu  bis  cenu  chloroethyl  chloroethylnitrosourea  complementing  confirm  correlations  cytotoxicity  deficiency  excision  innate  lines  methylguanine  methyltransferase  mgmt  modifying  nitrosourea  nucleotide  o6  poor  repair  resistance  rich  rodent  sensitivity  uv  xpd 
Tagcloud (Difference) ?
accumulation  alternative  attractive  deletion  drugs  enhancing  inactivation  involving  isg15  isgylation  multistep  native  oncogene  oncogenes  p53  promoting  propose  regulate  src  stability  suppressing  suppressor  suppressors  transformation  transformed  tumorigenesis  turn  tyr126  tyr220 
bcnu  bis  cenu  chloroethyl  chloroethylnitrosourea  complementing  confirm  correlations  cytotoxicity  deficiency  excision  innate  lines  methylguanine  methyltransferase  mgmt  modifying  nitrosourea  nucleotide  o6  poor  repair  resistance  rich  rodent  sensitivity  uv  xpd 
Tagcloud (Intersection) ?