RSL24D1 and PEA15

Number of citations: 50 (PubMedID 24710276)
Data Source: BioGRID (two hybrid)

		RSL24D1	PEA15
Name		ribosomal L24 domain containing 1	proliferation and apoptosis adaptor protein 15
Structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex
	Molecular Function	Structural Constituent Of Ribosome Protein Binding	Protein Binding
	Biological Process	Ribosome Biogenesis Ribosomal Large Subunit Biogenesis	MAPK Cascade Apoptotic Process Regulation Of Apoptotic Process Negative Regulation Of D-glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways		None	RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs		(S)-3-phenyllactic acid Anisomycin Puromycin	None
GWAS		Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes ( 29221444 ) Neutrophil count ( 21507922 ) Proteinuria in chronic kidney disease ( 26420894 )	No GWAS studies recorded
Interacting Genes		7 interacting genes: CDC23 DNMT3L FAM9B FBXO7 LSM8 MCPH1 PEA15	40 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RPSA RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13
Entrez ID		51187	8682
HPRD ID		12665	04579
Ensembl ID		ENSG00000137876	ENSG00000162734
Uniprot IDs		Q9UHA3	B1AKZ4 B1AKZ5 Q15121 Q96FS5
PDB IDs		6LSS 6LU8 8FKP 8FKQ 8FKR 8FKS 8FKT 8FKU 8FKV 8FKW 8FKX 8FKY 8FKZ 8FL0 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8IDT 8IDY 8IE3 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR1 8IR3 8RL2	4IZ5 4IZA 6P6B 6P6C
GO Terms Enriched among Interactors		Nucleoplasm Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite	Insulin-like Growth Factor Receptor Signaling Pathway Protein Serine Kinase Activity Cytosol Cytoplasm Protein Serine/threonine Kinase Activity Response To Epidermal Growth Factor Positive Regulation Of Macrophage Differentiation Regulation Of Golgi Organization Kinase Activity Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Execution Phase Of Apoptosis Interleukin-34-mediated Signaling Pathway Protein Kinase Activity ERBB Signaling Pathway Phosphate-containing Compound Metabolic Process Positive Regulation Of Cell Migration Response To Peptide Response To Cytokine Regulation Of Cellular Response To Stress Negative Regulation Of Programmed Cell Death Insulin Receptor Signaling Pathway Execution Phase Of Apoptosis Death Effector Domain Binding Regulation Of Macrophage Differentiation Regulation Of Golgi Inheritance Neural Crest Cell Development ATP Binding Positive Regulation Of Cell Motility Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Positive Regulation Of Locomotion Stem Cell Development Ripoptosome CD95 Death-inducing Signaling Complex Phospholipase D Activity Lipopolysaccharide-mediated Signaling Pathway RNA (guanine-N7)-methylation Death-inducing Signaling Complex Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Regulation Of Telomere Maintenance Regulation Of DNA Metabolic Process Negative Regulation Of Apoptotic Process Protein Phosphorylation Protein Autophosphorylation Response To Tumor Necrosis Factor Vascular Endothelial Cell Response To Laminar Fluid Shear Stress TRAIL-activated Apoptotic Signaling Pathway Outer Ear Morphogenesis ERBB3 Signaling Pathway