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DNAJB1 and FANCC
Number of citations of the paper that reports this interaction (PubMedID
11500375
)
56
Data Source:
HPRD
(in vitro)
DNAJB1
FANCC
Description
DnaJ heat shock protein family (Hsp40) member B1
FA complementation group C
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Postsynaptic Density
Neuronal Cell Body
Dendritic Spine
Sperm Head
Extracellular Exosome
Postsynapse
Glutamatergic Synapse
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Fanconi Anaemia Nuclear Complex
Molecular Function
ATPase Activator Activity
Transcription Corepressor Activity
Protein Binding
Hsp70 Protein Binding
Protein Folding Chaperone
Cadherin Binding
Unfolded Protein Binding
Protein-folding Chaperone Binding
ATPase Binding
Transcription Regulator Inhibitor Activity
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Protein Folding
Response To Unfolded Protein
Forebrain Development
Cellular Response To Heat
Negative Regulation Of Inclusion Body Assembly
Regulation Of Cellular Response To Heat
Positive Regulation Of Protein Folding
DNA Repair
Nucleotide-excision Repair
DNA Damage Response
Cellular Response To Oxidative Stress
Interstrand Cross-link Repair
Protein-containing Complex Assembly
Pathways
Regulation of HSF1-mediated heat shock response
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Attenuation phase
HSF1-dependent transactivation
MAPK6/MAPK4 signaling
Fanconi Anemia Pathway
TP53 Regulates Transcription of DNA Repair Genes
PKR-mediated signaling
Drugs
Diseases
Fanconi anemia
GWAS
Adventurousness (
30643258
)
General risk tolerance (MTAG) (
30643258
)
Birth weight (
31043758
)
Hematocrit (
32888494
)
Offspring birth weight (
31043758
)
Polycystic ovary syndrome (
26284813
)
Interacting Genes
33 interacting genes:
A2M
AKT1
ANK2
APP
BDKRB1
BRCA1
BRMS1
CEBPA
CENPE
CYP2C8
DNAJC3
DYRK3
ECSIT
FANCA
FANCC
GLB1
GSK3A
HSF1
HSPA1A
MAST1
NQO1
NRAS
PEA15
PLEKHO1
PPDPF
PSEN2
PTGES3
SOD1
SPP1
STUB1
TERF1
TTLL12
ZFP36
54 interacting genes:
APC
AZIN1
BMPR1A
BUB1
CAPN10
CCNA2
CCND1
CDK1
CTBP1
DLC1
DNAJB1
EGFR
FANCA
FANCD2
FANCE
FANCF
FANCG
FBXW7
GSTP1
HSP90AA1
HSP90B1
HSPA1A
HSPA4
HSPA8
IK
KRAS
KRT1
MEOX2
MLH3
MT-ATP6
MUTYH
NRAS
PDGFRL
PIK3CA
PMS2
POR
PRDX3
PRPF31
PTPN12
PTPRJ
RB1
RPL18
RPS3A
SMAD4
SPTA1
SPTAN1
SRC
STAT1
STMN1
STMN2
TCERG1
TGFBR2
USP14
ZBTB32
Entrez ID
3337
2176
HPRD ID
05198
01967
Ensembl ID
ENSG00000132002
ENSG00000158169
Uniprot IDs
P25685
Q6FHS4
A0A024R9N2
A0A087WW44
B4E3W2
Q00597
PDB IDs
1HDJ
2QLD
3AGX
3AGY
3AGZ
4WB7
6BYR
6WJF
6WJG
6Z5N
7NDX
8FE2
8FE5
8FEC
7KZP
7KZQ
7KZR
7KZS
7KZT
7KZV
Enriched GO Terms of Interacting Partners
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Enzyme Binding
Regulation Of Programmed Cell Death
Regulation Of Growth
Regulation Of Apoptotic Process
Intracellular Signal Transduction
Response To Temperature Stimulus
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Response To Heat
Cellular Response To Metal Ion
Protein-folding Chaperone Binding
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Response To Lipid
Regulation Of Developmental Growth
Positive Regulation Of Proteolysis
Positive Regulation Of Proteasomal Protein Catabolic Process
Positive Regulation Of Protein Catabolic Process
Response To Steroid Hormone
Intracellular Signaling Cassette
Misfolded Protein Binding
Positive Regulation Of Macromolecule Metabolic Process
Cytoplasm
Negative Regulation Of Programmed Cell Death
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Regulation Of Protein Catabolic Process
Regulation Of Cellular Response To Stress
Positive Regulation Of Apoptotic Process
Heat Shock Protein Binding
Regulation Of Apoptotic Signaling Pathway
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Catabolic Process
Response To Peptide
Regulation Of Cell Growth
Protein-containing Complex
Positive Regulation Of Gene Expression
Regulation Of Extrinsic Apoptotic Signaling Pathway
Negative Regulation Of Cell Growth
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Metabolic Process
Response To Hormone
Cellular Response To Topologically Incorrect Protein
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Regulation Of Defense Response
Regulation Of Cell Development
Signal Transduction
Regulation Of Cell Cycle
Response To Stress
Regulation Of Cellular Component Organization
Regulation Of Immune System Process
Negative Regulation Of Apoptotic Process
Cytosol
Regulation Of Programmed Cell Death
Regulation Of Cell Population Proliferation
Regulation Of Apoptotic Process
Negative Regulation Of Supramolecular Fiber Organization
Cellular Response To Stress
Response To Stress
Cellular Response To Growth Factor Stimulus
Negative Regulation Of Cellular Component Organization
Negative Regulation Of Cytoskeleton Organization
Response To Hormone
Response To Growth Factor
Fanconi Anaemia Nuclear Complex
Cellular Response To Peptide Hormone Stimulus
ATP-dependent Protein Folding Chaperone
Cellular Response To Hormone Stimulus
Interstrand Cross-link Repair
Nucleoplasm
Regulation Of Supramolecular Fiber Organization
Response To Steroid Hormone
Regulation Of Organelle Organization
Negative Regulation Of Programmed Cell Death
Cadherin Binding
Positive Regulation Of Cell Population Proliferation
Nucleus
Focal Adhesion
Protein Folding Chaperone
Negative Regulation Of Apoptotic Process
Cellular Response To Oxygen-containing Compound
Regulation Of Multicellular Organismal Process
DNA Repair
Regulation Of Immune System Process
Negative Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Protein-containing Complex Disassembly
DNA Damage Response
Intracellular Signal Transduction
Response To Peptide Hormone
Regulation Of Cytoskeleton Organization
Response To Lipid
G1/S Transition Of Mitotic Cell Cycle
Nucleic Acid Metabolic Process
Macromolecule Metabolic Process
Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Cell Cycle Phase Transition
Cell Cycle G1/S Phase Transition
Response To Unfolded Protein
Regulation Of Cellular Component Organization
Regulation Of Cell Cycle Phase Transition
Regulation Of Protein Depolymerization
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Tagcloud (Intersection)
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