HOXA10 and EMX1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		HOXA10	EMX1
Gene Name		homeobox A10	empty spiracles homeobox 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Transcription Factor Complex Cytoplasm	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Binding Histone Deacetylase Binding	Protein Binding Sequence-specific DNA Binding
	Biological Process	Skeletal System Development Transcription, DNA-templated Multicellular Organismal Development Spermatogenesis Single Fertilization Male Gonad Development Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Embryonic Limb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Uterus Development	In Utero Embryonic Development Regulation Of Transcription, DNA-templated Post-embryonic Development Cerebral Cortex Regionalization Cerebral Cortex Neuron Differentiation Response To Drug Brain Morphogenesis Neuron Projection Extension
Pathways
Drugs
Diseases
GWAS		Dental caries ( 23259602)
Protein-Protein Interactions		12 interactors: CREBBP EMX1 EP300 FOXO1 GMNN MEIS1 PBX1 POLR3D PTPN6 SIRT2 SNAPC1 SPI1	7 interactors: ALX4 ELK1 GTF2A1L HOXA10 POLR2D PRDM4 TP63
Entrez ID		3206	2016
HPRD ID		00845	08963
Ensembl ID		ENSG00000253293	ENSG00000135638
Uniprot IDs		P31260	Q04741
PDB IDs
Enriched GO Terms of Interacting Partners?		Immune System Process Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Response To Oxygen Levels Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Nitrogen Compound Metabolic Process Cell Development Protein Acetylation Negative Regulation Of Cell Differentiation N-terminal Peptidyl-lysine Acetylation Stem Cell Maintenance Positive Regulation Of Transcription, DNA-templated Innate Immune Response Organ Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Gene Expression Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Anatomical Structure Morphogenesis Gene Expression Multicellular Organismal Development Stem Cell Development Regulation Of Gene Expression Peptidyl-lysine Modification Cellular Macromolecule Biosynthetic Process Anatomical Structure Development Negative Regulation Of Transcription, DNA-templated Macromolecule Biosynthetic Process Positive Regulation Of Type I Interferon Production Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Stem Cell Differentiation N-terminal Protein Amino Acid Acetylation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Immune Response Developmental Process Regulation Of Type I Interferon Production Negative Regulation Of Gene Expression System Development Defense Response	Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Embryonic Limb Morphogenesis Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Limb Morphogenesis Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Limb Development Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Proximal/distal Pattern Formation Response To Gamma Radiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Pattern Specification Process Positive Regulation Of Transcription, DNA-templated Ectoderm And Mesoderm Interaction Epidermal Cell Division Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex Regulation Of Metabolic Process Hair Follicle Development Hair Cycle Process Skeletal System Development Hair Cycle Cellular Response To Testosterone Stimulus Squamous Basal Epithelial Stem Cell Differentiation Involved In Prostate Gland Acinus Development MRNA Export From Nucleus In Response To Heat Stress Embryonic Morphogenesis Digestive Tract Development Cellular Response To Radiation Response To Ionizing Radiation Digestive System Development Regulation Of Epidermal Cell Division Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process
Tagcloud ?		contrary coordination definitive drives e2 elevate epigenetic eralpha ere ere1 ere2 eres extensively h3k4 haematopoiesis homeobox knockdown leukaemia lineage methylase mll mll1 much oestrogen recruiting start suppresses transcriptionally way	124a accumulate annually appearing authentic cancers defect discontinued endoscopic endoscopy endpoint enrolled enrolment epigenetic excluding field gastric helicobacter metachronous multicentre nkx6 planned preselected pylori quartile takes trends undergone univariate
Tagcloud (Difference) ?		contrary coordination definitive drives e2 elevate eralpha ere ere1 ere2 eres extensively h3k4 haematopoiesis homeobox knockdown leukaemia lineage methylase mll mll1 much oestrogen recruiting start suppresses transcriptionally way	124a accumulate annually appearing authentic cancers defect discontinued endoscopic endoscopy endpoint enrolled enrolment excluding field gastric helicobacter metachronous multicentre nkx6 planned preselected pylori quartile takes trends undergone univariate
Tagcloud (Intersection) ?		epigenetic