PAM16 and BLOC1S2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		PAM16	BLOC1S2
Gene Name		presequence translocase-associated motor 16 homolog (S. cerevisiae)	biogenesis of lysosomal organelles complex-1, subunit 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Presequence Translocase-associated Import Motor Mitochondrial Inner Membrane Presequence Translocase Complex Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane Protein Complex	Gamma-tubulin Complex Nucleus Mitochondrion Centrosome BLOC-1 Complex Recycling Endosome
	Molecular Function	Protein Binding	Protein Binding Protein C-terminus Binding Gamma-tubulin Binding
	Biological Process	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix Negative Regulation Of ATPase Activity Cellular Protein Metabolic Process	Microtubule Nucleation Anterograde Axon Cargo Transport Positive Regulation Of Cell Proliferation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Neuron Projection Development Melanosome Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ARL6IP1 BLOC1S2 CEP70 DNAJC19 DNMT3B FEZ1 GPM6A MRFAP1 PGRMC1	15 interactors: APP BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 FAM9B HMOX2 MEST PAM16 RDH11 SNAPIN TNNT1 WASH1
Entrez ID		51025	282991
HPRD ID		14798	12526
Ensembl ID		ENSG00000217930
Uniprot IDs		I3L3T0 Q9Y3D7	F1T0F0 Q6QNY1
PDB IDs
Enriched GO Terms of Interacting Partners?		Generation Of Neurons Neurogenesis Neuron Projection Development Neuron Development Neuron Differentiation Cell Projection Organization Nervous System Development System Development Movement Of Cell Or Subcellular Component Neuron Projection Morphogenesis S-adenosylmethioninamine Metabolic Process Mitochondrial Transport Multicellular Organismal Development DNA Methylation On Cytosine Within A CG Sequence Anatomical Structure Development Cell Development C-5 Methylation Of Cytosine S-adenosylhomocysteine Metabolic Process Cell Projection Morphogenesis Cell Differentiation Cell Part Morphogenesis Methylation-dependent Chromatin Silencing Establishment Of Localization In Cell Developmental Process Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Positive Regulation Of Cell Projection Organization Cell Morphogenesis Negative Regulation Of Histone H3-K9 Methylation DNA Methylation On Cytosine Negative Regulation Of Macroautophagy Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Establishment Of Organelle Localization Positive Regulation Of Neuron Differentiation Cellular Localization Positive Regulation Of Histone H3-K4 Methylation Establishment Of Mitochondrion Localization Protein Complex Localization Negative Regulation Of Histone Methylation Positive Regulation Of Mitochondrial Membrane Permeability Locomotion Axon Guidance Anterograde Synaptic Vesicle Transport Mitochondrion Organization Melanosome Organization Microtubule Nucleation Pigment Granule Organization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Neurogenesis Regulation Of Histone H3-K4 Methylation	Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Pigment Granule Maturation Endosome To Melanosome Transport Establishment Of Organelle Localization Intracellular Transport Cellular Pigment Accumulation Organelle Localization Microtubule-based Process Endosomal Transport Neuron Projection Development Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Neuron Development Synaptic Transmission Cellular Localization Neuron Differentiation Cell Projection Organization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Secretion Of Lysosomal Enzymes Cell-cell Signaling Secretion By Cell Developmental Pigmentation Generation Of Neurons Neurogenesis Golgi Vesicle Transport Platelet Dense Granule Organization Secretion Cell Development Positive Regulation Of Pigment Cell Differentiation Cytoplasmic Transport Transport Exocytosis
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