PAM16 and PGRMC1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		PAM16	PGRMC1
Description		presequence translocase associated motor 16	progesterone receptor membrane component 1
Image		No pdb structure
GO Annotations	Cellular Component	PAM Complex, Tim23 Associated Import Motor Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Matrix Membrane Protein-containing Complex Matrix Side Of Mitochondrial Inner Membrane	Extracellular Region Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Plasma Membrane Endomembrane System Membrane Smooth Endoplasmic Reticulum Membrane Specific Granule Membrane Neuron Projection Neuronal Cell Body Cell Body Synapse
	Molecular Function	Protein Binding	Amyloid-beta Binding Steroid Binding Protein Binding Lipid Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding
	Biological Process	Ossification Intracellular Protein Transport Protein Transport Protein Import Into Mitochondrial Matrix Negative Regulation Of ATP-dependent Activity	Heme Biosynthetic Process Axon Guidance Memory Associative Learning Modification Of Synaptic Structure Positive Regulation Of Lipoprotein Transport Positive Regulation Of Protein Localization To Plasma Membrane Negative Regulation Of Synapse Organization
Pathways		Mitochondrial protein import	Neutrophil degranulation
Drugs			Dextromethorphan Nortriptyline Sertraline
Diseases
GWAS		Erectile dysfunction ( 30583798) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Hodgkin's lymphoma ( 34216518)
Interacting Genes		9 interacting genes: ARL6IP1 BLOC1S2 CEP70 DNMT3B FEZ1 GPM6A MEOX2 MRFAP1 PGRMC1	20 interacting genes: BIK CAMLG CCDC134 CENPU CIAO1 CREB3L1 DEFB124 EVI2B GET3 GLP1R GOLM1 KASH5 KCNE5 LINC00632 MTNR1A PAM16 SCAP SGTB TMEM213 ZNF71
Entrez ID		51025	10857
HPRD ID		14798	02338
Ensembl ID		ENSG00000217930	ENSG00000101856
Uniprot IDs		Q9Y3D7	O00264 Q6IB11
PDB IDs			4X8Y
Enriched GO Terms of Interacting Partners?		Gamma-tubulin Binding Plasma Membrane Bounded Cell Projection Organization Neuron Projection Development Cell Projection Organization DNA (cytosine-5-)-methyltransferase Activity, Acting On CpG Substrates Positive Regulation Of Anterograde Axonal Transport Of Mitochondrion Neuronal Cell Body	GET Complex
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