PAM16 and PGRMC1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		PAM16	PGRMC1
Gene Name		presequence translocase-associated motor 16 homolog (S. cerevisiae)	progesterone receptor membrane component 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Presequence Translocase-associated Import Motor Mitochondrial Inner Membrane Presequence Translocase Complex Mitochondrial Matrix Extrinsic Component Of Mitochondrial Inner Membrane Protein Complex	Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Steroid Binding Protein Binding Heme Binding
	Biological Process	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix Negative Regulation Of ATPase Activity Cellular Protein Metabolic Process	Axon Guidance
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: ARL6IP1 BLOC1S2 CEP70 DNAJC19 DNMT3B FEZ1 GPM6A MRFAP1 PGRMC1	5 interactors: CENPU CREB3L1 MTNR1A PAM16 SCAP
Entrez ID		51025	10857
HPRD ID		14798	02338
Ensembl ID		ENSG00000217930	ENSG00000101856
Uniprot IDs		I3L3T0 Q9Y3D7	O00264 Q6IB11
PDB IDs
Enriched GO Terms of Interacting Partners?		Generation Of Neurons Neurogenesis Neuron Projection Development Neuron Development Neuron Differentiation Cell Projection Organization Nervous System Development System Development Movement Of Cell Or Subcellular Component Neuron Projection Morphogenesis S-adenosylmethioninamine Metabolic Process Mitochondrial Transport Multicellular Organismal Development DNA Methylation On Cytosine Within A CG Sequence Anatomical Structure Development Cell Development C-5 Methylation Of Cytosine S-adenosylhomocysteine Metabolic Process Cell Projection Morphogenesis Cell Differentiation Cell Part Morphogenesis Methylation-dependent Chromatin Silencing Establishment Of Localization In Cell Developmental Process Mitochondrial Outer Membrane Permeabilization Platelet Dense Granule Organization Positive Regulation Of Cell Projection Organization Cell Morphogenesis Negative Regulation Of Histone H3-K9 Methylation DNA Methylation On Cytosine Negative Regulation Of Macroautophagy Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Establishment Of Organelle Localization Positive Regulation Of Neuron Differentiation Cellular Localization Positive Regulation Of Histone H3-K4 Methylation Establishment Of Mitochondrion Localization Protein Complex Localization Negative Regulation Of Histone Methylation Positive Regulation Of Mitochondrial Membrane Permeability Locomotion Axon Guidance Anterograde Synaptic Vesicle Transport Mitochondrion Organization Melanosome Organization Microtubule Nucleation Pigment Granule Organization Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Positive Regulation Of Neurogenesis Regulation Of Histone H3-K4 Methylation	ER-nucleus Signaling Pathway Negative Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Protein Import Into Mitochondrial Matrix Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process SREBP Signaling Pathway Negative Regulation Of ATPase Activity Positive Regulation Of Receptor Biosynthetic Process Response To Sterol Depletion Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Regulation Of Receptor Biosynthetic Process Positive Regulation Of CGMP Biosynthetic Process Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of CGMP Metabolic Process Regulation Of CGMP Biosynthetic Process Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Steroid Metabolic Process CENP-A Containing Nucleosome Assembly Regulation Of Cholesterol Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Regulation Of CGMP Metabolic Process Histone Exchange Mating Behavior DNA Replication-independent Nucleosome Assembly Regulation Of Nitrogen Compound Metabolic Process Regulation Of ATPase Activity Negative Regulation Of Lipid Biosynthetic Process Centromere Complex Assembly Intracellular Protein Transmembrane Transport Positive Regulation Of Cellular Metabolic Process
Tagcloud ?			abeta25 ag205 alleviated attempted attenuate attenuates brings broadly classic complementary entitled exerts inhibiting insults jnk mitochondria nervous neuroprotection neuroprotections neuroprotective neurosteroid pr progesterone protected protective rescuing ru486 special steroids
Tagcloud (Difference) ?			abeta25 ag205 alleviated attempted attenuate attenuates brings broadly classic complementary entitled exerts inhibiting insults jnk mitochondria nervous neuroprotection neuroprotections neuroprotective neurosteroid pr progesterone protected protective rescuing ru486 special steroids
Tagcloud (Intersection) ?