ADGRB2 and HDHD2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		ADGRB2	HDHD2
Description		adhesion G protein-coupled receptor B2	haloacid dehalogenase like hydrolase domain containing 2
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane Synapse Glutamatergic Synapse	Cytoplasm Extracellular Exosome
	Molecular Function	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding	Protein Binding Phosphatase Activity Enzyme Binding Metal Ion Binding
	Biological Process	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Peripheral Nervous System Development Negative Regulation Of Angiogenesis Calcineurin-NFAT Signaling Cascade Positive Regulation Of Synapse Assembly
Pathways
Drugs
Diseases
GWAS		Asthma ( 31959851) Intraocular pressure ( 29617998 29785010) Smoking status (ever vs never smokers) ( 30643258) Walking pace ( 33128006)	Blood protein levels ( 30072576) Fruit consumption ( 32066663)
Interacting Genes		9 interacting genes: ARHGAP1 DLG4 GABPB1 HDHD2 LRP2BP SHANK1 SHANK2 SNTA1 STARD13	12 interacting genes: ADGRB2 CFD CRMP1 DVL1 EPHB6 LUC7L2 MEOX2 MGST2 PIP5K1C SOD2 TARBP2 TRAPPC11
Entrez ID		576	84064
HPRD ID		04063	13640
Ensembl ID		ENSG00000121753	ENSG00000167220
Uniprot IDs		A2A3C1 O60241	Q9H0R4 V9HW73
PDB IDs		8OEK	3HLT
Enriched GO Terms of Interacting Partners?		Vocalization Behavior Ionotropic Glutamate Receptor Binding Learning Synaptic Receptor Adaptor Activity Social Behavior Learning Or Memory Associative Learning Cognition SH3 Domain Binding Dendritic Spine Morphogenesis Dendritic Spine Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Ionotropic Glutamate Receptor Signaling Pathway Excitatory Synapse Positive Regulation Of Excitatory Postsynaptic Potential Dendritic Spine Organization Ligand-gated Ion Channel Signaling Pathway Neuron Projection Organization Postsynapse Organization Postsynaptic Membrane Neuromuscular Process Controlling Balance Modulation Of Excitatory Postsynaptic Potential Glutamate Receptor Signaling Pathway Postsynaptic Density Negative Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Cell Migration Involved In Sprouting Angiogenesis P2Y1 Nucleotide Receptor Binding Protein Localization To Synapse Determination Of Affect Somatostatin Receptor Binding Scaffold Protein Binding Negative Regulation Of Endothelial Cell Migration Neuron Projection Neuromuscular Junction Protein Localization To Cell Junction PDZ Domain Binding Endothelial Tube Lumen Extension System Process Negative Regulation Of Endocytic Recycling Beta-1 Adrenergic Receptor Binding Regulation Of Grooming Behavior Nervous System Process Lactose Synthase Activity Structural Constituent Of Postsynaptic Density Regulation Of Nervous System Process Regulation Of Membrane Potential Neuromuscular Process Syntrophin Complex N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity
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