PTPRB and CNTNAP1

Number of citations of the paper that reports this interaction (PMID 9118959)
84

Data Source:
HPRD (in vivo)

		PTPRB	CNTNAP1
Gene Name		protein tyrosine phosphatase, receptor type, B	contactin associated protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Receptor Complex	Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Integral Component Of Membrane Paranode Region Of Axon
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding	Receptor Activity SH3/SH2 Adaptor Activity Protein Binding SH3 Domain Binding
	Biological Process	Angiogenesis Protein Dephosphorylation Phosphate-containing Compound Metabolic Process Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Protein Localization To Paranode Region Of Axon Cytoskeleton Organization Cell Adhesion Signal Transduction Axon Guidance Axon Cargo Transport Positive Regulation Of Signal Transduction Neuronal Action Potential Propagation Paranodal Junction Assembly Neuron Projection Morphogenesis Neuromuscular Process Controlling Posture Neuromuscular Process Controlling Balance
Pathways			Axon guidance Neurofascin interactions L1CAM interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CDH5 CNTN1 CNTNAP1 F11R GHR MAGI3 MET NRCAM TEK TNC	8 interactors: CDC42 FYN NFASC PTPRB RAC1 RHOA RTN4 SRC
Entrez ID		5787	8506
HPRD ID		01474	03825
Ensembl ID		ENSG00000127329	ENSG00000108797
Uniprot IDs		B7ZKS8 F5H3G6 P23467 Q86VA4	P78357
PDB IDs		2AHS 2H02 2H03 2H04 2HC1 2HC2 2I3R 2I3U 2I4E 2I4G 2I4H 2I5X
Enriched GO Terms of Interacting Partners?		Cell Adhesion Signaling Cell Communication Cell Development Axon Development Locomotion Neuronal Action Potential Propagation Cell Morphogenesis Involved In Differentiation Neuron Projection Development Movement Of Cell Or Subcellular Component Axon Guidance Mesenchymal-epithelial Cell Signaling Enzyme Linked Receptor Protein Signaling Pathway Neuron Development Positive Regulation Of MAPK Cascade Response To Stimulus Positive Regulation Of Kinase Activity Cell Morphogenesis Axonogenesis Neuron Differentiation Cell Projection Organization Positive Regulation Of Transferase Activity Cell Junction Assembly Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cellular Response To Stimulus Cell-cell Junction Organization Positive Regulation Of MAP Kinase Activity Regulation Of MAPK Cascade Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Anatomical Structure Development Cell Differentiation Positive Regulation Of Metabolic Process Regulation Of Establishment Or Maintenance Of Cell Polarity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Protein Phosphorylation Anatomical Structure Morphogenesis Signal Transduction Endothelial Cell Development Positive Regulation Of Protein Serine/threonine Kinase Activity Peptidyl-tyrosine Phosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of Catalytic Activity Regulation Of Kinase Activity Generation Of Neurons Developmental Process Positive Regulation Of Intracellular Signal Transduction Transmission Of Nerve Impulse	Axon Development Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Morphogenesis Involved In Differentiation Neuron Projection Development Axon Guidance Neuron Development Regulation Of Cell Projection Organization Cell Morphogenesis Cell-cell Junction Organization Neurotrophin TRK Receptor Signaling Pathway Axonogenesis Neurotrophin Signaling Pathway Neuron Differentiation Cell Projection Organization Cell Morphogenesis Involved In Neuron Differentiation T Cell Costimulation Chemotaxis Locomotion Neuron Projection Morphogenesis Anatomical Structure Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Movement Of Cell Or Subcellular Component Brain Development Head Development Generation Of Neurons Cell Migration Cell Projection Morphogenesis Cell Part Morphogenesis Neurogenesis Positive Regulation Of Phosphatidylinositol 3-kinase Activity Cell Motility Enzyme Linked Receptor Protein Signaling Pathway Blood Coagulation Hemostasis Cell Development Central Nervous System Development Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cell Morphogenesis Platelet Activation Positive Regulation Of T Cell Activation Cellular Response To Growth Factor Stimulus Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Body Fluid Levels Regulation Of Phosphatidylinositol 3-kinase Activity Response To Growth Factor Leukocyte Migration Wound Healing
Tagcloud ?		accumulative acknowledged astrocytoma chi3l1 chr1 chr22 clustering crocc daughter discover ecm exome gbm hereditary lymphatic multiforme narrow pilocytic players pms2 pontine predisposition proximity q12 siblings snvs striking synonymous underline
Tagcloud (Difference) ?		accumulative acknowledged astrocytoma chi3l1 chr1 chr22 clustering crocc daughter discover ecm exome gbm hereditary lymphatic multiforme narrow pilocytic players pms2 pontine predisposition proximity q12 siblings snvs striking synonymous underline
Tagcloud (Intersection) ?