PTPRB and CNTN1

Number of citations of the paper that reports this interaction (PMID 7628014)
56

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		PTPRB	CNTN1
Gene Name		protein tyrosine phosphatase, receptor type, B	contactin 1
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Receptor Complex	Plasma Membrane Membrane Anchored Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding	Glycoprotein Binding Carbohydrate Binding
	Biological Process	Angiogenesis Protein Dephosphorylation Phosphate-containing Compound Metabolic Process Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Cell Adhesion Notch Signaling Pathway Axon Guidance Positive Regulation Of Gene Expression Positive Regulation Of Sodium Ion Transport Positive Regulation Of Neuron Projection Development Cerebellum Development
Pathways			Signaling by NOTCH1 HD Domain Mutants in Cancer Axon guidance Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer Signaling by NOTCH L1CAM interactions NOTCH2 Activation and Transmission of Signal to the Nucleus Activated NOTCH1 Transmits Signal to the Nucleus Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant Signaling by NOTCH2 Neurofascin interactions Signaling by NOTCH1 Signaling by NOTCH1 PEST Domain Mutants in Cancer Signaling by NOTCH1 in Cancer FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS			Protein quantitative trait loci ( 18464913)
Protein-Protein Interactions		10 interactors: CDH5 CNTN1 CNTNAP1 F11R GHR MAGI3 MET NRCAM TEK TNC	12 interactors: CNTN2 FYN L1CAM MAPK6 NOTCH1 NOTCH2 PPP1CA PRNP PTPRB SCNN1B TNC TNR
Entrez ID		5787	1272
HPRD ID		01474	07189
Ensembl ID		ENSG00000127329	ENSG00000018236
Uniprot IDs		B7ZKS8 F5H3G6 P23467 Q86VA4	Q12860
PDB IDs		2AHS 2H02 2H03 2H04 2HC1 2HC2 2I3R 2I3U 2I4E 2I4G 2I4H 2I5X	2EE2 3S97
Enriched GO Terms of Interacting Partners?		Cell Adhesion Signaling Cell Communication Cell Development Axon Development Locomotion Neuronal Action Potential Propagation Cell Morphogenesis Involved In Differentiation Neuron Projection Development Movement Of Cell Or Subcellular Component Axon Guidance Mesenchymal-epithelial Cell Signaling Enzyme Linked Receptor Protein Signaling Pathway Neuron Development Positive Regulation Of MAPK Cascade Response To Stimulus Positive Regulation Of Kinase Activity Cell Morphogenesis Axonogenesis Neuron Differentiation Cell Projection Organization Positive Regulation Of Transferase Activity Cell Junction Assembly Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cellular Response To Stimulus Cell-cell Junction Organization Positive Regulation Of MAP Kinase Activity Regulation Of MAPK Cascade Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Anatomical Structure Development Cell Differentiation Positive Regulation Of Metabolic Process Regulation Of Establishment Or Maintenance Of Cell Polarity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Protein Phosphorylation Anatomical Structure Morphogenesis Signal Transduction Endothelial Cell Development Positive Regulation Of Protein Serine/threonine Kinase Activity Peptidyl-tyrosine Phosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of Catalytic Activity Regulation Of Kinase Activity Generation Of Neurons Developmental Process Positive Regulation Of Intracellular Signal Transduction Transmission Of Nerve Impulse See more	Axon Development Anatomical Structure Morphogenesis Response To External Stimulus Neuron Projection Development Axonogenesis Neuron Development Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Cell Adhesion Neuron Projection Morphogenesis Neuron Differentiation Cell Projection Organization Cell Development Cell Morphogenesis Involved In Differentiation Axon Guidance System Development Cell Projection Morphogenesis Cell Part Morphogenesis Negative Regulation Of Cell Adhesion Nervous System Development Generation Of Neurons Response To Stimulus Neurogenesis Multicellular Organismal Development Cell Morphogenesis Anatomical Structure Development Response To Growth Factor Chemotaxis Learning Or Memory Interleukin-4 Secretion Notch Signaling Involved In Heart Development Pulmonary Valve Morphogenesis Cognition Locomotion Interleukin-4 Production Positive Regulation Of Signal Transduction Developmental Process Organ Development Regulation Of Signaling Regulation Of Cell-cell Adhesion Cell Migration Response To Ethanol Regulation Of Cell Proliferation Movement Of Cell Or Subcellular Component Learning Cell Motility Forebrain Development Cell Differentiation Single-organism Behavior Notch Receptor Processing Regulation Of Cell Morphogenesis See more
Tagcloud ?		accumulative acknowledged astrocytoma chi3l1 chr1 chr22 clustering crocc daughter discover ecm exome gbm hereditary lymphatic multiforme narrow pilocytic players pms2 pontine predisposition proximity q12 siblings snvs striking synonymous underline	axin2 axonogenesis coding dendritogenesis interplay inverse maintaining maturing microrna micrornas mrnas ncam1 negr1 neurite neurotrophin nrxn1 ontology orchestrated prkcb pruning represented respective rnas sh2b3 synaptogenesis temporally tightly transcriptome verification
Tagcloud (Difference) ?		accumulative acknowledged astrocytoma chi3l1 chr1 chr22 clustering crocc daughter discover ecm exome gbm hereditary lymphatic multiforme narrow pilocytic players pms2 pontine predisposition proximity q12 siblings snvs striking synonymous underline	axin2 axonogenesis coding dendritogenesis interplay inverse maintaining maturing microrna micrornas mrnas ncam1 negr1 neurite neurotrophin nrxn1 ontology orchestrated prkcb pruning represented respective rnas sh2b3 synaptogenesis temporally tightly transcriptome verification
Tagcloud (Intersection) ?