PTPRB and MAGI3

Number of citations of the paper that reports this interaction (PMID 12615970)
14

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		PTPRB	MAGI3
Gene Name		protein tyrosine phosphatase, receptor type, B	membrane associated guanylate kinase, WW and PDZ domain containing 3
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Receptor Complex	Nucleus Plasma Membrane Tight Junction Membrane
	Molecular Function	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding	Guanylate Kinase Activity Frizzled Binding Protein Binding ATP Binding Protein Complex Scaffold
	Biological Process	Angiogenesis Protein Dephosphorylation Phosphate-containing Compound Metabolic Process Dephosphorylation Peptidyl-tyrosine Dephosphorylation	Apoptotic Process Viral Process Intracellular Signal Transduction Positive Regulation Of JUN Kinase Activity Nucleotide Phosphorylation
Pathways
Drugs
Diseases
GWAS			Bulimia nervosa ( 23568457) Obesity-related traits ( 23251661)
Protein-Protein Interactions		10 interactors: CDH5 CNTN1 CNTNAP1 F11R GHR MAGI3 MET NRCAM TEK TNC	14 interactors: ADRB1 BAI1 DSCAML1 FZD4 FZD7 GRIN2B LATS1 NRCAM PLXNB3 PTEN PTPRB TGFA TNK2 VANGL2
Entrez ID		5787	260425
HPRD ID		01474	11290
Ensembl ID		ENSG00000127329	ENSG00000081026
Uniprot IDs		B7ZKS8 F5H3G6 P23467 Q86VA4	Q5TCQ9
PDB IDs		2AHS 2H02 2H03 2H04 2HC1 2HC2 2I3R 2I3U 2I4E 2I4G 2I4H 2I5X	3SOE
Enriched GO Terms of Interacting Partners?		Cell Adhesion Signaling Cell Communication Cell Development Axon Development Locomotion Neuronal Action Potential Propagation Cell Morphogenesis Involved In Differentiation Neuron Projection Development Movement Of Cell Or Subcellular Component Axon Guidance Mesenchymal-epithelial Cell Signaling Enzyme Linked Receptor Protein Signaling Pathway Neuron Development Positive Regulation Of MAPK Cascade Response To Stimulus Positive Regulation Of Kinase Activity Cell Morphogenesis Axonogenesis Neuron Differentiation Cell Projection Organization Positive Regulation Of Transferase Activity Cell Junction Assembly Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Cellular Response To Stimulus Cell-cell Junction Organization Positive Regulation Of MAP Kinase Activity Regulation Of MAPK Cascade Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Anatomical Structure Development Cell Differentiation Positive Regulation Of Metabolic Process Regulation Of Establishment Or Maintenance Of Cell Polarity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Protein Phosphorylation Anatomical Structure Morphogenesis Signal Transduction Endothelial Cell Development Positive Regulation Of Protein Serine/threonine Kinase Activity Peptidyl-tyrosine Phosphorylation Regulation Of MAP Kinase Activity Positive Regulation Of Catalytic Activity Regulation Of Kinase Activity Generation Of Neurons Developmental Process Positive Regulation Of Intracellular Signal Transduction Transmission Of Nerve Impulse	Cell Morphogenesis Developmental Process Cell Morphogenesis Involved In Differentiation Neuron Differentiation Anatomical Structure Morphogenesis Cell Differentiation Generation Of Neurons System Development Neurogenesis Signaling Negative Regulation Of Cell Adhesion Cell Communication Cell Development Cell Projection Morphogenesis Cell Part Morphogenesis Multicellular Organismal Development Axonogenesis Anatomical Structure Development Neuron Development Axon Development Regulation Of Phosphorus Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Non-canonical Wnt Signaling Pathway Signal Transduction Nervous System Development Neuron Projection Morphogenesis Cell Surface Receptor Signaling Pathway Cell Projection Organization Locomotion Blood Vessel Morphogenesis Negative Regulation Of Cell-substrate Adhesion Regulation Of Phosphorylation Regulation Of Cellular Component Organization Neuron Projection Development Positive Regulation Of Phosphorylation Cardiovascular System Development Positive Regulation Of Protein Modification Process Blood Vessel Development Response To Stimulus Vasculature Development Cellular Response To Stimulus Regulation Of Postsynaptic Membrane Potential Wnt Signaling Pathway Regulation Of Catalytic Activity Regulation Of Protein Phosphorylation Multicellular Organismal Response To Stress Regulation Of Cell Adhesion Regulation Of Epithelial Cell Proliferation Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud ?		accumulative acknowledged astrocytoma chi3l1 chr1 chr22 clustering crocc daughter discover ecm exome gbm hereditary lymphatic multiforme narrow pilocytic players pms2 pontine predisposition proximity q12 siblings snvs striking synonymous underline	aberration akt1 akt3 amplifications beyond cbfb competitive confirming deaths deletions discovered erbb2 exome gata3 genomes malignancy map3k1 mexico million notably oestrogen pairs partner pik3ca rearrangements recurrent runx1 somatic vietnam
Tagcloud (Difference) ?		accumulative acknowledged astrocytoma chi3l1 chr1 chr22 clustering crocc daughter discover ecm gbm hereditary lymphatic multiforme narrow pilocytic players pms2 pontine predisposition proximity q12 siblings snvs striking synonymous underline	aberration akt1 akt3 amplifications beyond cbfb competitive confirming deaths deletions discovered erbb2 gata3 genomes malignancy map3k1 mexico million notably oestrogen pairs partner pik3ca rearrangements recurrent runx1 somatic vietnam
Tagcloud (Intersection) ?		exome