PAFAH1B3 and ECH1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PAFAH1B3	ECH1
Gene Name		platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	enoyl CoA hydratase 1, peroxisomal
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Membrane Extracellular Vesicular Exosome	Mitochondrion Peroxisome Membrane Extracellular Vesicular Exosome
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity	Receptor Binding Protein Binding Isomerase Activity
	Biological Process	Lipid Metabolic Process Spermatogenesis Nervous System Development Brain Development Lipid Catabolic Process	Fatty Acid Beta-oxidation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		33 interactors: BRD7 C14orf1 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 PAFAH1B1 PAFAH1B2 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1	13 interactors: APP CSTF2 EEF1D EEF1G FAM9B HTT PAFAH1B3 PEX5 SERPINB9 STAT3 TIMP1 TLR10 TRAF1
Entrez ID		5050	1891
HPRD ID		04354	02825
Ensembl ID		ENSG00000079462	ENSG00000104823
Uniprot IDs		Q15102	Q13011
PDB IDs			2VRE
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Transcription, DNA-templated Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance RNA Biosynthetic Process Regulation Of Chromosome Organization Telomere Maintenance Negative Regulation Of Gene Expression Cell Division Negative Regulation Of DNA Metabolic Process RNA Metabolic Process Cell Separation After Cytokinesis Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Telomere Maintenance Negative Regulation Of Transcription, DNA-templated RNA-dependent DNA Replication Negative Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Response To X-ray Cellular Macromolecule Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Mitotic Cell Cycle Phase Transition Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Fibroblast Proliferation Biosynthetic Process Macromolecule Biosynthetic Process Response To Salt Stress Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Stem Cell Division Chromosome Organization Mitotic Cell Cycle Process Negative Regulation Of Clathrin-mediated Endocytosis Peptidyl-cysteine S-trans-nitrosylation Negative Regulation Of DNA Recombination At Telomere Regulation Of Mitotic Cell Cycle Negative Regulation Of DNA Replication Gene Expression Mitotic Cell Cycle Neuron Apoptotic Process Cellular Response To Ionizing Radiation Negative Regulation Of Transcription From RNA Polymerase II Promoter 'de Novo' Posttranslational Protein Folding Metabolic Process	Regulation Of Developmental Growth Regulation Of Multicellular Organism Growth Protein Import Central Nervous System Development MRNA Polyadenylation Response To Estrogen RNA Polyadenylation Regulation Of Growth Endoplasmic Reticulum Organization Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Axon Cargo Transport Mating Negative Regulation Of Neurogenesis Mitochondrial Membrane Organization Neuron Apoptotic Process Brain Development Visual Learning Sexual Reproduction Head Development Visual Behavior Neuron Death Neural Plate Formation Negative Regulation Of Cell Development Platelet Degranulation Regulation Of Cell Death Negative Regulation Of Proteolysis Establishment Of Protein Localization To Organelle Negative Regulation Of Protein Processing MRNA 3'-end Processing Associative Learning Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Response To Hormone Regulation Of Peptidase Activity Negative Regulation Of Protein Homotetramerization Synaptic Growth At Neuromuscular Junction Serotonin Uptake Lactate Biosynthetic Process From Pyruvate Apoptotic Process Negative Regulation Of Cell Death Protein Targeting Feeding Behavior Programmed Cell Death Forebrain Development Regulation Of Signal Transduction RNA 3'-end Processing Reproduction Cell Death
Tagcloud ?		abpp acetylhydrolase acyl aided campaign carbamate carbamoylation cherry endeavored fluopol hits house hts hydrolase hydrolases medchem ml256 mudpit oxidatively phospholipids picked pla2g7 scaffold sid tunable	33k butylhydroperoxide choline coa disturbed enoyl galactosidase hayflick hmsc hmscs hydratase hyperoxia inducer metabolites mlc2 myosin p30 peroxisomal premature prosomal psma1 replicative senescence shares shortening sips spots sublethal tert
Tagcloud (Difference) ?		abpp acetylhydrolase acyl aided campaign carbamate carbamoylation cherry endeavored fluopol hits house hts hydrolase hydrolases medchem ml256 mudpit oxidatively phospholipids picked pla2g7 scaffold sid tunable	33k butylhydroperoxide choline coa disturbed enoyl galactosidase hayflick hmsc hmscs hydratase hyperoxia inducer metabolites mlc2 myosin p30 peroxisomal premature prosomal psma1 replicative senescence shares shortening sips spots sublethal tert
Tagcloud (Intersection) ?