PAFAH1B3

Description		platelet activating factor acetylhydrolase 1b catalytic subunit 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Membrane
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Hydrolase Activity Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity
	Biological Process	Lipid Metabolic Process Spermatogenesis Nervous System Development Lipid Catabolic Process
Pathways		COPI-independent Golgi-to-ER retrograde traffic
Drugs		(1R)-1,2,2-trimethylpropyl (R)-methylphosphinate
Diseases
GWAS
Interacting Genes		37 interacting genes: BRD7 CCDC90B CHMP7 COPS6 CRMP1 DDX24 ECH1 EEF1A1 ERG28 FXR1 GAPDH GBP2 GDF9 HSPH1 IGSF21 LNX1 LRIF1 MED31 MEI4 NIF3L1 PAFAH1B1 PAFAH1B2 PICK1 PLEKHM1 RBM48 SDCBP2 SETDB1 SUMO4 TERF1 TERF2IP TLE1 TP53 TUBB2A UNC119 XRCC6 ZBTB16 ZHX1
Entrez ID		5050
HPRD ID		04354
Ensembl ID		ENSG00000079462
Uniprot IDs		A0A024R0L6 Q15102
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear Telomere Cap Complex Identical Protein Binding 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Telomeric DNA Binding Protein Heterodimerization Activity Negative Regulation Of Telomere Maintenance Shelterin Complex Nucleolus Double-stranded Telomeric DNA Binding G-rich Strand Telomeric DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Telomere Capping
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