PAFAH1B2 and PPP1R12C

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PAFAH1B2	PPP1R12C
Description		platelet activating factor acetylhydrolase 1b catalytic subunit 2	protein phosphatase 1 regulatory subunit 12C
Image			No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Extracellular Region Nucleolus Cytoplasm Cytosol Plasma Membrane 1-alkyl-2-acetylglycerophosphocholine Esterase Complex Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Stress Fiber Cytoplasm Cytoskeleton
	Molecular Function	1-alkyl-2-acetylglycerophosphocholine Esterase Activity Protein Binding Hydrolase Activity Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding Protein Heterodimerization Activity Platelet-activating Factor Acetyltransferase Activity	Enzyme Inhibitor Activity Protein Binding Myosin Phosphatase Regulator Activity Phosphatase Regulator Activity Protein Kinase Binding
	Biological Process	Lipid Metabolic Process Spermatogenesis Lipid Catabolic Process Positive Regulation Of Macroautophagy	Signal Transduction Neuron Projection Morphogenesis
Pathways		Neutrophil degranulation COPI-independent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Adult body size ( 32376654) Blood protein levels ( 23696881) HDL cholesterol ( 24507774) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Protein quantitative trait loci ( 18464913) Refractive error ( 32231278) Systolic blood pressure ( 30578418)
Interacting Genes		19 interacting genes: ACIN1 ASF1A CCT3 CLVS2 CRK PAFAH1B1 PAFAH1B3 PINX1 PPP1R12C PRKN REXO1 RPLP0 SLA SNUPN STAT3 TIMM50 TRIM55 TRIM63 ZFP36L1	27 interacting genes: AIRIM ATP6V1H ATXN7 BHLHA9 CACNA1A CCDC185 CDC42BPA EHHADH EXOC3 FMR1 FXR1 FXR2 IL16 IMP3 MPRIP MYL2 NOD2 NXF1 PAFAH1B2 PPP1CB RBM17 SMAD3 SMARCA2 SPECC1L THOC1 TSFM USHBP1
Entrez ID		5049	54776
HPRD ID		03940	11452
Ensembl ID		ENSG00000168092	ENSG00000125503
Uniprot IDs		P68402 V9HW44	Q9BZL4
PDB IDs		1VYH
Enriched GO Terms of Interacting Partners?		1-alkyl-2-acetylglycerophosphocholine Esterase Complex Positive Regulation Of Monocyte Differentiation Response To Transforming Growth Factor Beta Cellular Response To Transforming Growth Factor Beta Stimulus Diapedesis Reelin-mediated Signaling Pathway Protein Localization To Organelle Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of ATP Biosynthetic Process Negative Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Monocyte Differentiation Regulation Of ATP Biosynthetic Process Negative Regulation Of Glycolytic Process Positive Regulation Of Myeloid Cell Differentiation Phospholipase Binding Negative Regulation Of ATP Metabolic Process Response To Glucocorticoid Intracellular Protein Localization Response To Hormone Microtubule Nucleus Regulation Of JNK Cascade Protein-containing Complex Binding Response To Corticosteroid Negative Regulation Of JNK Cascade Positive Regulation Of Cell Growth Positive Regulation Of ATP Metabolic Process Negative Regulation Of Phosphate Metabolic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process Protein Localization To Mitochondrion Regulation Of Reactive Oxygen Species Biosynthetic Process RNA Binding Cell Population Proliferation Organelle Organization Negative Regulation Of Spontaneous Neurotransmitter Secretion Protein Localization To Nucleus Regulation Of Telomere Maintenance Via Telomerase Phosphotyrosine Residue Binding Regulation Of Myeloid Cell Differentiation Nuclear-transcribed MRNA Catabolic Process, Deadenylation-independent Decay Cellular Response To Raffinose Positive Regulation Of Myeloid Leukocyte Differentiation Regulation Of Erythrocyte Differentiation Response To Steroid Hormone Helper T Cell Diapedesis Leukocyte Migration Positive Regulation Of Protein Localization Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin	Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Long-term Neuronal Synaptic Plasticity MRNA Transport Translation Regulator Activity RNA Transport Regulation Of Long-term Neuronal Synaptic Plasticity Cytoplasmic Stress Granule Nucleobase-containing Compound Transport RNA Strand Annealing Activity Presynaptic Modulation Of Chemical Synaptic Transmission Intracellular Membraneless Organelle Regulation Of Neuronal Synaptic Plasticity MRNA Export From Nucleus Positive Regulation Of MiRNA-mediated Gene Silencing Transcription Export Complex Cytosol Protein Heterodimerization Activity Positive Regulation Of Interleukin-1 Production RNA Export From Nucleus Cytoplasmic Ribonucleoprotein Granule Nucleolus MRNA Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Interleukin-1 Production Positive Regulation Of Positive Chemotaxis Dentate Gyrus Development Regulation Of Post-transcriptional Gene Silencing Nuclear Export MRNA 3'-UTR Binding Negative Regulation Of Microtubule Depolymerization Protein Binding Positive Regulation Of Intracellular Transport Of Viral Material Negative Regulation Of Lung Blood Pressure Nuclear Mineralocorticoid Receptor Binding Muscle Cell Fate Specification Myosin-light-chain-phosphatase Activity Regulation Of Microtubule Depolymerization Neural Crest Cell Delamination Detection Of Muramyl Dipeptide Muramyl Dipeptide Binding Positive Regulation Of Catabolic Process Cytoplasm Neuron Projection Nucleic Acid Binding RNA Binding Positive Regulation Of Translation
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