OAZ2 and BDKRB1

Number of citations: 90 (PubMedID 28298427)
Data Source: BioGRID (two hybrid)

		OAZ2	BDKRB1
Name		ornithine decarboxylase antizyme 2	bradykinin receptor B1
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Protein Binding Ornithine Decarboxylase Inhibitor Activity	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding
	Biological Process	Biogenic Amine Metabolic Process Polyamine Metabolic Process Polyamine Biosynthetic Process Positive Regulation Of Protein Catabolic Process Viral Translational Frameshifting Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport	Positive Regulation Of Leukocyte Migration Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Mechanical Stimulus Cell Migration Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs		None	Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
GWAS		Aluminium levels ( 26025379 ) Neuroticism ( 29255261 )	Metabolite levels ( 23823483 )
Interacting Genes		5 interacting genes: BDKRB1 CDR2 OAZ1 ODC1 SYTL3	32 interacting genes: CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C LTAP1 MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22
Entrez ID		4947	623
HPRD ID		11966	02639
Ensembl ID		ENSG00000180304	ENSG00000100739
Uniprot IDs		O95190	P46663
PDB IDs		Not available	7EIB
GO Terms Enriched among Interactors		Polyamine Biosynthetic Process Polyamine Metabolic Process Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Biogenic Amine Metabolic Process Amine Metabolic Process Bradykinin Receptor Activity Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Ornithine Decarboxylase Activity Putrescine Biosynthetic Process From Arginine, Via Ornithine Signal Peptidase Complex Putrescine Biosynthetic Process Viral Translational Frameshifting Putrescine Metabolic Process Signal Peptide Processing Neurexin Family Protein Binding	Endoplasmic Reticulum Membrane Membrane Ferrous Iron Transmembrane Transporter Activity Brain Development Iron Ion Transmembrane Transporter Activity Negative Regulation Of Transport Profilin Binding