BDKRB1 and SLC39A14

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		BDKRB1	SLC39A14
Description		bradykinin receptor B1	solute carrier family 39 member 14
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Membrane	Lysosome Lysosomal Membrane Endosome Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane Early Endosome Membrane Late Endosome Membrane
	Molecular Function	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding	Iron Ion Transmembrane Transporter Activity Manganese Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transporter Activity Protein Binding Cadmium Ion Transmembrane Transporter Activity Ferrous Iron Transmembrane Transporter Activity Monoatomic Anion:monoatomic Cation Symporter Activity Metal Ion Transmembrane Transporter Activity Monoatomic Cation:bicarbonate Symporter Activity
	Biological Process	Positive Regulation Of Leukocyte Migration Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Mechanical Stimulus Cell Migration Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Chondrocyte Differentiation Gluconeogenesis Monoatomic Ion Transport Iron Ion Transport Zinc Ion Transport Intracellular Zinc Ion Homeostasis Insulin Receptor Signaling Pathway Regulation Of Hormone Levels Bicarbonate Transport Metal Ion Transport Intracellular Monoatomic Cation Homeostasis Cellular Response To Insulin Stimulus Iron Import Into Cell Iron Ion Transmembrane Transport Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Manganese Ion Homeostasis Transmembrane Transport Cadmium Ion Transmembrane Transport Cellular Response To Glucose Stimulus Manganese Ion Transmembrane Transport Zinc Ion Transmembrane Transport Zinc Ion Import Across Plasma Membrane Monoatomic Anion Transmembrane Transport Inorganic Cation Transmembrane Transport Import Across Plasma Membrane
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Zinc influx into cells by the SLC39 gene family
Drugs		Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Metabolite levels ( 23823483)	B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio ( 29237677) Verbal declarative memory ( 25648963)
Interacting Genes		32 interacting genes: CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C LTAP1 MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22	3 interacting genes: BDKRB1 LZTS2 SEPTIN3
Entrez ID		623	23516
HPRD ID		02639	12288
Ensembl ID		ENSG00000100739	ENSG00000104635
Uniprot IDs		P46663	A0A0S2Z534 Q15043
PDB IDs		7EIB
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Ferrous Iron Transmembrane Transporter Activity Brain Development Iron Ion Transmembrane Transporter Activity Negative Regulation Of Transport Profilin Binding	Cytoskeleton-dependent Cytokinesis Primary Ureteric Bud Growth Bradykinin Receptor Activity N-acetyllactosamine Synthase Activity Beta-N-acetylglucosaminylglycopeptide Beta-1,4-galactosyltransferase Activity Lactose Synthase Activity Galactosyltransferase Activity Ureter Morphogenesis Microtubule Severing Cerebellar Purkinje Cell Layer Development Septin Ring Septin Complex Spindle Midzone Assembly Cell Division Site Cell Division
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