BDKRB1 and RETREG1

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		BDKRB1	RETREG1
Description		bradykinin receptor B1	reticulophagy regulator 1
Image
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Membrane	Nucleolus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cis-Golgi Network Membrane Nuclear Body
	Molecular Function	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding	Protein Binding Endoplasmic Reticulum-autophagosome Adaptor Activity
	Biological Process	Positive Regulation Of Leukocyte Migration Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Mechanical Stimulus Cell Migration Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Mitophagy Autophagy Endoplasmic Reticulum Organization Sensory Perception Of Pain Collagen Catabolic Process Negative Regulation Of Neuron Apoptotic Process White Fat Cell Differentiation Reticulophagy Substrate Localization To Autophagosome
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs		Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Metabolite levels ( 23823483)	Diffusing capacity of carbon monoxide ( 30694715) Orofacial cleft x maternal periconceptional multivitamin use interaction (1df) ( 33937227)
Interacting Genes		32 interacting genes: CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C LTAP1 MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22	7 interacting genes: AMFR APP BDKRB1 GABARAPL2 MAP1LC3B MORC3 SNAPIN
Entrez ID		623	54463
HPRD ID		02639	07879
Ensembl ID		ENSG00000100739	ENSG00000154153
Uniprot IDs		P46663	A0A804HHX5 Q9H6L5
PDB IDs		7EIB	7BRQ 7FB5
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Ferrous Iron Transmembrane Transporter Activity Brain Development Iron Ion Transmembrane Transporter Activity Negative Regulation Of Transport Profilin Binding	Autophagosome Maturation Cellular Response To Nitrogen Starvation Phosphatidylethanolamine Binding Protein-containing Complex Disassembly Vacuole Organization Response To Stress Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cytoplasmic Vesicle Mitophagy Autophagosome Membrane Autophagy Of Mitochondrion SNARE Binding Positive Regulation Of Late Endosome To Lysosome Transport Axo-dendritic Transport Autophagosome Protein-folding Chaperone Binding Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Bradykinin Receptor Activity Autophagosome Organization Autophagosome Assembly Golgi Apparatus PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Phospholipid Binding Negative Regulation Of Canonical Wnt Signaling Pathway Protein-containing Complex Organization Growth Cone BAT3 Complex Binding Regulation Of Calcium Ion Transmembrane Transport Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Positive Regulation Of Leukocyte Migration Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Endoplasmic Reticulum Negative Regulation Of Wnt Signaling Pathway
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