BDKRB1 and NAP1L4

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		BDKRB1	NAP1L4
Description		bradykinin receptor B1	nucleosome assembly protein 1 like 4
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Membrane	Chromatin Nucleus Cytoplasm Dendrite Neuronal Cell Body
	Molecular Function	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding	Chromatin Binding RNA Binding Protein Binding Nucleosome Binding Histone Binding Unfolded Protein Binding
	Biological Process	Positive Regulation Of Leukocyte Migration Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Mechanical Stimulus Cell Migration Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Nucleosome Assembly
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs		Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Metabolite levels ( 23823483)	Aspartate aminotransferase levels ( 33547301) Calcium levels ( 20705733) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Malaria ( 31844061) Monocyte count ( 32888494) Neutrophil count ( 32888494) Platelet distribution width ( 32888494) White blood cell count ( 32888494)
Interacting Genes		32 interacting genes: CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C LTAP1 MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22	16 interacting genes: BDKRB1 CSNK2A1 CSNK2A2 EP300 ESR1 H1-1 H2AC20 H2AC8 H2BC21 H3-4 H3C14 H4C14 LINC01554 MTNR1A OGT UBC
Entrez ID		623	4676
HPRD ID		02639	11873
Ensembl ID		ENSG00000100739	ENSG00000205531
Uniprot IDs		P46663	Q99733
PDB IDs		7EIB
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Ferrous Iron Transmembrane Transporter Activity Brain Development Iron Ion Transmembrane Transporter Activity Negative Regulation Of Transport Profilin Binding	Structural Constituent Of Chromatin Nucleosome Chromatin Organization Chromatin Remodeling Protein-DNA Complex Assembly Protein Localization To Chromosome Nucleosome Assembly Chromosome Nucleosome Organization Protein Localization To Chromatin Protein Heterodimerization Activity Protein Kinase CK2 Complex Rhythmic Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Localization To Organelle Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process DNA Binding Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Chromatin DNA Binding Protein-containing Complex Assembly Cellular Component Assembly Nucleoplasm CENP-A Containing Nucleosome Protein Localization To CENP-A Containing Chromatin Protein-containing Complex Organization Negative Regulation Of Macromolecule Metabolic Process Sin3-type Complex Negative Regulation Of Protein Catabolic Process Histone Acetyltransferase Complex Circadian Rhythm Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process PcG Protein Complex Negative Regulation Of Metabolic Process Negative Regulation Of Proteolysis Negative Regulation Of Catabolic Process Nucleus Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein Localization To Chromosome, Centromeric Region Transcription Coregulator Binding Negative Regulation Of Translational Initiation Regulation Of Proteasomal Protein Catabolic Process Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity
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