BDKRB1 and SLC25A28

Number of citations of the paper that reports this interaction (PubMedID 28298427)
90

Data Source:
BioGRID (two hybrid)

		BDKRB1	SLC25A28
Description		bradykinin receptor B1	solute carrier family 25 member 28
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Membrane	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane
	Molecular Function	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding	Iron Ion Transmembrane Transporter Activity Ferrous Iron Transmembrane Transporter Activity
	Biological Process	Positive Regulation Of Leukocyte Migration Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Mechanical Stimulus Cell Migration Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol	Monoatomic Ion Transport Iron Ion Transport Iron Import Into The Mitochondrion
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events	Mitochondrial iron-sulfur cluster biogenesis
Drugs		Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Metabolite levels ( 23823483)	β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Colorectal cancer ( 24737748 25990418 26151821) Crohn's disease ( 22412388) Diverticular disease ( 30177863)
Interacting Genes		32 interacting genes: CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C LTAP1 MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22	2 interacting genes: BDKRB1 CRYAA
Entrez ID		623	81894
HPRD ID		02639	15359
Ensembl ID		ENSG00000100739	ENSG00000155287
Uniprot IDs		P46663	A0A8V8TR30 Q96A46
PDB IDs		7EIB
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Membrane Membrane Ferrous Iron Transmembrane Transporter Activity Brain Development Iron Ion Transmembrane Transporter Activity Negative Regulation Of Transport Profilin Binding	Regulation Of Cell Growth Regulation Of Growth Bradykinin Receptor Activity Tubulin Complex Assembly Response To UV-A Lens Fiber Cell Morphogenesis Embryonic Camera-type Eye Morphogenesis Lens Morphogenesis In Camera-type Eye Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Peptide Binding Apoptotic Process Involved In Development Structural Constituent Of Eye Lens Embryonic Eye Morphogenesis Apoptotic Process Involved In Morphogenesis Protein Refolding Lens Development In Camera-type Eye Negative Regulation Of Blood Pressure
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