OAZ2 and ODC1

Number of citations: 0 (PubMedID 12359729)
Data Source: BioGRID (pull down), HPRD (in vitro)

		OAZ2	ODC1
Name		ornithine decarboxylase antizyme 2	ornithine decarboxylase 1
Structure		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Cytoplasm Cytosol
	Molecular Function	Protein Binding Ornithine Decarboxylase Inhibitor Activity	Catalytic Activity Ornithine Decarboxylase Activity Protein Binding Lyase Activity Carboxy-lyase Activity Protein Homodimerization Activity
	Biological Process	Biogenic Amine Metabolic Process Polyamine Metabolic Process Polyamine Biosynthetic Process Positive Regulation Of Protein Catabolic Process Viral Translational Frameshifting Positive Regulation Of Intracellular Protein Transport Negative Regulation Of Polyamine Transmembrane Transport	Kidney Development Polyamine Metabolic Process Polyamine Biosynthetic Process Cell Population Proliferation Positive Regulation Of Cell Population Proliferation Response To Virus Putrescine Biosynthetic Process From Arginine, Via Ornithine Regulation Of Protein Catabolic Process
Pathways		Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines	Regulation of ornithine decarboxylase (ODC) Metabolism of polyamines
Drugs		None	Pyridoxal phosphate Spermine Sildenafil Valproic acid Putrescine Pyridoxine phosphate N-Pyridoxyl-Glycine-5-Monophosphate L-Eflornithine N(6)-(pyridoxal phosphate)-L-lysine Geneticin Eflornithine
GWAS		Aluminium levels ( 26025379 ) Neuroticism ( 29255261 )	No GWAS studies recorded
Novel Interactors		1 novel interactors: SEC11A	None recorded
Interacting Genes		5 interacting genes: BDKRB1 CDR2 OAZ1 ODC1 SYTL3	17 interacting genes: BAAT CSNK2B GORASP2 HEMGN KAT5 MAP2K1 NANS OAZ1 OAZ2 RSC1A1 SSR1 STX17 TDRD7 TK1 TMOD1 TSTD2 ZNF510
Entrez ID		4947	4953
HPRD ID		11966	01324
Ensembl ID		ENSG00000180304	ENSG00000115758
Uniprot IDs		O95190	B4DXF8 P11926
PDB IDs		Not available	1D7K 2ON3 2OO0 4ZGY 5BWA 7S3F 7S3G 7U6P 7U6U 9B8M 9B8N
GO Terms Enriched among Interactors		Polyamine Biosynthetic Process Polyamine Metabolic Process Amine Biosynthetic Process Biogenic Amine Biosynthetic Process Biogenic Amine Metabolic Process Amine Metabolic Process Bradykinin Receptor Activity Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Ornithine Decarboxylase Activity Putrescine Biosynthetic Process From Arginine, Via Ornithine Signal Peptidase Complex Putrescine Biosynthetic Process Viral Translational Frameshifting Putrescine Metabolic Process Signal Peptide Processing Neurexin Family Protein Binding	Ornithine Decarboxylase Inhibitor Activity Negative Regulation Of Polyamine Transmembrane Transport Viral Translational Frameshifting Polyamine Biosynthetic Process Polyamine Metabolic Process Negative Regulation Of Transmembrane Transport Golgi Organization Viral Process Amine Biosynthetic Process Biogenic Amine Biosynthetic Process