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NPY and MEP1B
Number of citations of the paper that reports this interaction (PubMedID
11278902
)
0
Data Source:
HPRD
(in vitro)
NPY
MEP1B
Description
neuropeptide Y
meprin A subunit beta
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Golgi Apparatus
Cytoplasmic Vesicle
Terminal Bouton
Perikaryon
Perinuclear Region Of Cytoplasm
GABA-ergic Synapse
Neuronal Dense Core Vesicle
Extracellular Region
Extracellular Space
Plasma Membrane
Membrane
Meprin A Complex
Molecular Function
G Protein-coupled Receptor Binding
G Protein-coupled Receptor Activity
Signaling Receptor Binding
Hormone Activity
Neuropeptide Hormone Activity
Calcium Channel Regulator Activity
Protein Binding
Neuropeptide Y Receptor Binding
Metalloendopeptidase Activity
Protein Binding
Peptidase Activity
Metallopeptidase Activity
Zinc Ion Binding
Hydrolase Activity
Identical Protein Binding
Metal Ion Binding
Biological Process
Response To Yeast
Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Neuropeptide Signaling Pathway
Chemical Synaptic Transmission
Feeding Behavior
Regulation Of Blood Pressure
Positive Regulation Of Cell Population Proliferation
Adult Feeding Behavior
Positive Regulation Of Cell-substrate Adhesion
Antibacterial Humoral Response
Antifungal Humoral Response
Central Nervous System Neuron Development
Cerebral Cortex Development
Neuron Projection Development
Positive Regulation Of Appetite
Regulation Of Nerve Growth Factor Production
Monocyte Activation
Innate Immune Response
Negative Regulation Of Blood Pressure
Positive Regulation Of Dopamine Metabolic Process
Short-day Photoperiodism
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Intestinal Epithelial Cell Differentiation
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Presynaptic Cytosolic Calcium Ion Concentration
Synaptic Signaling Via Neuropeptide
Positive Regulation Of Eating Behavior
Positive Regulation Of Nitric Oxide Metabolic Process
Regulation Of Synaptic Vesicle Exocytosis
Proteolysis
Inflammatory Response
Pathways
Peptide ligand-binding receptors
G alpha (i) signalling events
FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes
Drugs
Phentermine
2-aminoisobutyric acid
L-tyrosinamide
Diseases
GWAS
Adiponectin levels (
33562295
)
Adult body size (
32376654
)
Age at first sexual intercourse (
34211149
)
Aggressive periodontitis (sex interaction) (
25256105
)
Body size at age 10 (
32376654
)
Chronotype (
30696823
)
Morning person (
30696823
)
Periodontitis (
23459936
)
Retinitis pigmentosa (
33514863
)
Vitamin D levels (
25208829
)
Metabolite levels (
23823483
)
TRAIL levels (
27989323
)
Interacting Genes
16 interacting genes:
ATP12A
BAG6
GHRL
MC4R
MEP1A
MEP1B
NPFF
NPFFR2
NPY1R
NPY2R
NPY4R
NPY5R
NR1H2
PMCH
UBQLN1
UBQLN2
13 interacting genes:
CCK
FN1
GAST
GCG
GRP
MEP1A
NPY
OS9
PRKACA
PRKCD
PYY
SCT
TSPAN8
Entrez ID
4852
4225
HPRD ID
01214
02667
Ensembl ID
ENSG00000122585
ENSG00000141434
Uniprot IDs
A4D158
P01303
J3QKX5
Q16820
PDB IDs
1QFA
1RON
7RTA
7VGX
7X9A
7X9B
7YOO
8K6M
8K6N
8K6O
4GWM
4GWN
7AQ1
7AUW
Enriched GO Terms of Interacting Partners
?
Neuropeptide Signaling Pathway
Neuropeptide Y Receptor Activity
Peptide YY Receptor Activity
Pancreatic Polypeptide Receptor Activity
Neuropeptide Binding
G Protein-coupled Receptor Signaling Pathway
Feeding Behavior
Negative Regulation Of Transport
Positive Regulation Of ERAD Pathway
G Protein-coupled Receptor Activity
Meprin A Complex
Regulation Of Response To Endoplasmic Reticulum Stress
Regulation Of ERAD Pathway
Regulation Of Feeding Behavior
Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep
Negative Regulation Of Synaptic Transmission
Polyubiquitin Modification-dependent Protein Binding
Positive Regulation Of Response To Endoplasmic Reticulum Stress
Positive Regulation Of Circadian Sleep/wake Cycle, Sleep
Signaling
Negative Regulation Of Secretion
Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep
Cell Communication
Regulation Of Eating Behavior
Outflow Tract Morphogenesis
Synaptic Signaling Via Neuropeptide
Peptide Hormone Secretion
Regulation Of Behavior
Peptide Secretion
Cardiac Left Ventricle Morphogenesis
Positive Regulation Of Digestive System Process
Hormone Secretion
ERAD Pathway
Peptide Transport
Regulation Of Response To Food
Hormone Transport
Regulation Of Secretion By Cell
Regulation Of Circadian Sleep/wake Cycle, Sleep
Neuropeptide Receptor Activity
Positive Regulation Of Circadian Rhythm
Positive Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Secretion
Regulation Of Circadian Sleep/wake Cycle
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Regulation Of Appetite
Synaptic Signaling
Positive Regulation Of Proteolysis Involved In Protein Catabolic Process
Signal Transduction
Amide Transport
Hormone Activity
Neuropeptide Hormone Activity
G Protein-coupled Receptor Signaling Pathway
Extracellular Space
Feeding Behavior
Positive Regulation Of Peptide Hormone Secretion
Positive Regulation Of Peptide Secretion
Neuropeptide Y Receptor Binding
Extracellular Region
Positive Regulation Of Hormone Secretion
Signaling Receptor Binding
Signal Transduction
Regulation Of Peptide Hormone Secretion
Regulation Of Biological Quality
G Protein-coupled Receptor Binding
Regulation Of Hormone Levels
Cellular Response To Glucagon Stimulus
Intestinal Epithelial Cell Differentiation
Regulation Of Hormone Secretion
Regulation Of Secretion By Cell
Regulation Of Body Fluid Levels
Regulation Of Transport
Positive Regulation Of Secretion By Cell
Neuropeptide Signaling Pathway
Positive Regulation Of Signal Transduction
Regulation Of Secretion
Positive Regulation Of Secretion
Response To Glucagon
Receptor Ligand Activity
Negative Regulation Of Multicellular Organismal Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Positive Regulation Of Gluconeogenesis
Regulation Of Appetite
Positive Regulation Of Lipid Metabolic Process
Regulation Of Intracellular Protein Transport
Positive Regulation Of Lipid Catabolic Process
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Behavior
Positive Regulation Of Transport
Regulation Of Protein Transport
Cellular Response To Peptide Hormone Stimulus
Peptidyl-serine Phosphorylation
Regulation Of Cellular Localization
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Glucose Metabolic Process
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
Regulation Of Gluconeogenesis
Short-day Photoperiodism
Negative Regulation Of Coagulation
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Tagcloud (Difference)
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Tagcloud (Intersection)
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