NFYB and YBX1

Number of citations of the paper that reports this interaction (PMID 7651426)
13

Data Source:
HPRD (in vitro)

		NFYB	YBX1
Gene Name		nuclear transcription factor Y, beta	Y box binding protein 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex	Nucleus Nucleoplasm U12-type Spliceosomal Complex Cytoplasm Cytoplasmic Stress Granule Ribonucleoprotein Complex Nuclear Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome CRD-mediated MRNA Stability Complex Histone Pre-mRNA 3'end Processing Complex
	Molecular Function	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Protein Complex Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Repressing Transcription Factor Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding Sequence-specific DNA Binding Transcription Factor Activity RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter MRNA Splicing, Via Spliceosome In Utero Embryonic Development Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Splicing Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cell Division CRD-mediated MRNA Stabilization
Pathways		PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins ATF4 activates genes ATF6-alpha activates chaperone genes Regulation of cholesterol biosynthesis by SREBP (SREBF) Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) PERK regulates gene expression ATF6-alpha activates chaperones Unfolded Protein Response (UPR)	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		24 interactors: AGTRAP C1QBP CEBPZ CIITA CNTN2 DRAP1 ELF1 EP300 GRB2 MAOB MYC NFYA NFYC POLE4 SMYD3 SP1 TAF11 TAF12 TAF6 TBP TP53 TP73 YBX1 YBX3	41 interactors: ACTA2 AKT1 ANKRD2 APBB1 CALM1 CSNK2A1 CTCF FBXO33 FMR1 FUS GSK3B HABP4 HIST1H1C HLA-C HNRNPD HNRNPK IL7R IREB2 IRF1 JAM2 LCP2 LSM3 MAPK1 NFYB PCBP2 PCNA PRPF40A PURA RBBP6 RPS6KA1 RPS6KA3 SLC6A4 SMAD3 SMU1 SREK1 SRSF9 TFAP2A TP53 TRAF6 UBC VEGFA
Entrez ID		4801	4904
HPRD ID		01794	01095
Ensembl ID		ENSG00000120837	ENSG00000065978
Uniprot IDs		P25208	P67809
PDB IDs		1N1J 4AWL	1H95
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Viral Process Cellular Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation By Host Of Viral Transcription Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Regulation Of Cellular Process Negative Regulation Of Cellular Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Interaction With Symbiont Negative Regulation Of Signal Transduction Cellular Response To Radiation Negative Regulation Of Signaling Response To Ionizing Radiation Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator	Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Regulation Of Immune Response Immune Response Regulation Of Immune System Process Negative Regulation Of Protein Metabolic Process Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Growth Factor Stimulus Positive Regulation Of Metabolic Process Immune System Process Response To Stress Neurotrophin TRK Receptor Signaling Pathway Response To Growth Factor Apoptotic Process Neurotrophin Signaling Pathway Innate Immune Response RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Growth Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Death Death Cell Activation Regulation Of Nitrogen Compound Metabolic Process Response To Abiotic Stimulus Regulation Of Cell Differentiation System Development Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Translation Negative Regulation Of Biosynthetic Process Gene Expression Blood Coagulation Hemostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Wound Healing Regulation Of DNA-templated Transcription In Response To Stress Positive Regulation Of Cell Growth Regulation Of RNA Metabolic Process Regulation Of Growth Posttranscriptional Regulation Of Gene Expression
Tagcloud ?		attenuates behave caf ccaat competes concordance conversely counteracts deacetylase deltanp73 deltanp73alpha detecting exist hdac hdac1 immunofluorescence motif nih3t3 p73 p73alpha pdgfrb periods repression starved supporting tap73 trichostatin yc	annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 xrcc5 yy1 zfhx3 zfp36 zmat3
Tagcloud (Difference) ?		attenuates behave caf ccaat competes concordance conversely counteracts deacetylase deltanp73 deltanp73alpha detecting exist hdac hdac1 immunofluorescence motif nih3t3 p73 p73alpha pdgfrb periods repression starved supporting tap73 trichostatin yc	annotation bub california cruz databases david deterioration downloaded exploring geo gse27567 h17 hub inheritance mendelian networks omim omnibus ranked santa topological visualization xpc xrcc4 xrcc5 yy1 zfhx3 zfp36 zmat3
Tagcloud (Intersection) ?