NELL2 and ATN1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		NELL2	ATN1
Gene Name		NEL-like 2 (chicken)	atrophin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Cell Junction Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding	Transcription Corepressor Activity Protein Binding Protein Domain Specific Binding Toxin Receptor Binding
	Biological Process	Neuron Cellular Homeostasis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Central Nervous System Development Toxin Metabolic Process Cell Migration Maintenance Of Cell Polarity Neuron Apoptotic Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ATN1 ATXN7 CACNA1A GFI1B PRKAR1A	93 interactors: AES AGRN ALG13 ARF3 ATRX BAG6 BAIAP2 CACNB1 CASP1 CASP3 CBFA2T2 CENPJ CHRD CRACR2A CRIP2 CTNND2 DMPK DVL1 DVL2 ECM1 EFEMP1 EFEMP2 EWSR1 FBLN1 FBLN2 FBLN5 GAPDH GCC1 GIGYF1 GRN HINFP HSPG2 ITCH JAG2 KAT6A KAT6B KAT7 KRT31 KRTAP4-12 LENG8 LRP2 LTBP1 LTBP4 LYST MAGI1 MAGI2 MAP7D1 MBP MDFI MEGF11 MEGF6 MEGF8 NCK2 NELL1 NELL2 NOC2L NR2E1 PCSK5 PDCD6IP PFKL PLSCR1 PRRC2A PRRC2B PSMA3 PSME3 RAD54L2 RBFOX1 RBFOX2 RBM10 RBPMS RCHY1 RERE RHOXF2 RNF115 RNF31 RUNX1T1 SIAH1 SIAH2 SLIT1 SPAG5 SSPO STXBP4 SYVN1 TEP1 TLE1 TRIP6 USP54 VIM WDR5 WWP1 WWP2 ZMYND8 ZSWIM8
Entrez ID		4753	1822
HPRD ID		11891	06311
Ensembl ID		ENSG00000184613	ENSG00000111676
Uniprot IDs		B7Z625 Q99435	P54259 Q86V38
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cerebellar Molecular Layer Development Energy Reserve Metabolic Process Vestibular Nucleus Development Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Regulation Of Insulin Secretion Gamma-aminobutyric Acid Secretion Regulation Of Peptide Hormone Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Rhythmic Synaptic Transmission Regulation Of Hormone Secretion Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of CAMP-dependent Protein Kinase Activity Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Biosynthetic Process Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Negative Regulation Of Hormone Biosynthetic Process Pons Development Maintenance Of Cell Polarity Negative Regulation Of Phosphorylation Regulation Of CAMP-dependent Protein Kinase Activity Regulation Of Protein Secretion Toxin Metabolic Process Generation Of Precursor Metabolites And Energy Activation Of Protein Kinase A Activity Cerebellar Purkinje Cell Differentiation Negative Regulation Of Meiotic Nuclear Division Regulation Of Metabolic Process Cerebellar Purkinje Cell Layer Morphogenesis Cardiac Muscle Cell Proliferation Growth Histone Deubiquitination System Development Reflex Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Meiotic Cell Cycle Regulation Of Transcription, DNA-templated Behavioral Response To Pain Regulation Of Cellular Component Organization Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Histone H3-K4 Methylation Neuromuscular Synaptic Transmission Regulation Of RNA Metabolic Process Regulation Of Hormone Biosynthetic Process	Regulation Of Cellular Process Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Multicellular Organismal Development Regulation Of Nitrogen Compound Metabolic Process Developmental Process Regulation Of Gene Expression Signaling Regulation Of Signaling Signal Transduction Nervous System Development Anatomical Structure Development Cell Communication Negative Regulation Of Signaling Negative Regulation Of Signal Transduction Regulation Of RNA Metabolic Process Cellular Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Extracellular Matrix Organization Extracellular Structure Organization Cellular Protein Catabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of Proteolysis Regulation Of RNA Biosynthetic Process System Development Response To Stimulus Cell Death Death Ubiquitin-dependent Protein Catabolic Process Anatomical Structure Morphogenesis Modification-dependent Protein Catabolic Process Protein Catabolic Process Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Programmed Cell Death Regulation Of Transcription, DNA-templated Regulation Of Signal Transduction Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Cellular Component Organization Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Biosynthetic Process Protein Ubiquitination Axon Development
Tagcloud ?		antiapoptotic apoptotic caspases chaperones chop cleaved context continuous cos7 cytoprotective decreasing ebp endoplasmic environments er homeostasis homologous inducer intra pro protection reticulum stress stresses thapsigargin triggers u0126 unfolded xl	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Difference) ?		antiapoptotic apoptotic caspases chaperones chop cleaved context continuous cos7 cytoprotective decreasing ebp endoplasmic environments er homeostasis homologous inducer intra pro protection reticulum stress stresses thapsigargin triggers u0126 unfolded xl	atrophin1 atrophy chip cortical degenerative demethylase dentatorubral depletion h3k4 hint inducing knockout lbal lsd1 lysine maintenance methylation npc pallidoluysian phenocopied poorly precise premature progenitor repression rescued seq surprisingly tranylcypromine
Tagcloud (Intersection) ?