NELL2 and GFI1B

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		NELL2	GFI1B
Gene Name		NEL-like 2 (chicken)	growth factor independent 1B transcription repressor
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Nucleus Transcription Factor Complex Nuclear Matrix
	Molecular Function	Calcium Ion Binding Protein Binding	RNA Polymerase II Transcription Factor Binding DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Neuron Cellular Homeostasis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell Proliferation Chromatin Modification Hemopoiesis Regulation Of Histone H3-K4 Methylation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ATN1 ATXN7 CACNA1A GFI1B PRKAR1A	71 interactors: ACTN1 AES AGPAT6 AGRN AJUBA ANKS3 ATXN2 BECN1 BEGAIN BEND5 BRCA1 BRE CCDC136 CCDC85B CENPB CENPJ COPS5 DNAJA3 DTNA DZANK1 EFEMP1 EFEMP2 EGFL7 FBLN1 FBLN5 GRIP2 GRN HECW1 HGS HNRNPK HSPG2 IFFO1 JAG2 KALRN KIF17 LAMB1 LTBP4 LZTS2 MATR3 MEGF6 MEGF8 MID2 MON1A MYH14 NELL1 NELL2 NOTCH1 NSMF PDE4DIP PDLIM5 PDZD4 PHC2 PICK1 PSMA3 RAB11FIP4 RCHY1 RINT1 RNF31 RUNDC3A TAF1 TMF1 TNS2 TRAF1 TRIM27 TRIP6 TSPYL2 TXNDC11 USHBP1 VSNL1 ZNRD1 ZNRF3
Entrez ID		4753	8328
HPRD ID		11891	05088
Ensembl ID		ENSG00000184613	ENSG00000165702
Uniprot IDs		B7Z625 Q99435	Q5VTD9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cerebellar Molecular Layer Development Energy Reserve Metabolic Process Vestibular Nucleus Development Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Regulation Of Insulin Secretion Gamma-aminobutyric Acid Secretion Regulation Of Peptide Hormone Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Rhythmic Synaptic Transmission Regulation Of Hormone Secretion Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of CAMP-dependent Protein Kinase Activity Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Biosynthetic Process Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Negative Regulation Of Hormone Biosynthetic Process Pons Development Maintenance Of Cell Polarity Negative Regulation Of Phosphorylation Regulation Of CAMP-dependent Protein Kinase Activity Regulation Of Protein Secretion Toxin Metabolic Process Generation Of Precursor Metabolites And Energy Activation Of Protein Kinase A Activity Cerebellar Purkinje Cell Differentiation Negative Regulation Of Meiotic Nuclear Division Regulation Of Metabolic Process Cerebellar Purkinje Cell Layer Morphogenesis Cardiac Muscle Cell Proliferation Growth Histone Deubiquitination System Development Reflex Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Meiotic Cell Cycle Regulation Of Transcription, DNA-templated Behavioral Response To Pain Regulation Of Cellular Component Organization Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Histone H3-K4 Methylation Neuromuscular Synaptic Transmission Regulation Of RNA Metabolic Process Regulation Of Hormone Biosynthetic Process	Regulation Of Cellular Process Cell Communication Regulation Of Cellular Component Organization Regulation Of Signaling Extracellular Matrix Organization Extracellular Structure Organization Signaling Cellular Response To Stimulus Signal Transduction Response To Stimulus Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Signal Transduction Regulation Of Growth Negative Regulation Of Wnt Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Regulation Of Canonical Wnt Signaling Pathway Developmental Process Secretion Negative Regulation Of Signaling Regulation Of Locomotion Cellular Process Regulation Of Cellular Component Movement Focal Adhesion Assembly Protein Localization Protein Ubiquitination Cellular Localization Negative Regulation Of Signal Transduction Regulation Of Protein Metabolic Process Regulation Of Wnt Signaling Pathway Protein Modification By Small Protein Conjugation Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Cell-substrate Adhesion Adherens Junction Assembly Cell Differentiation Cellular Component Assembly Neurogenesis Auditory Receptor Cell Fate Commitment Anatomical Structure Development Regulation Of Gene Expression Regulation Of Proteolysis Regulation Of Apoptotic Process Cell-substrate Junction Assembly Regulation Of I-kappaB Kinase/NF-kappaB Signaling Secretion By Cell Regulation Of Cell Proliferation Receptor Clustering Regulation Of Vesicle-mediated Transport
Tagcloud ?		antiapoptotic apoptotic caspases chaperones chop cleaved context continuous cos7 cytoprotective decreasing ebp endoplasmic environments er homeostasis homologous inducer intra pro protection reticulum stress stresses thapsigargin triggers u0126 unfolded xl	appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge
Tagcloud (Difference) ?		antiapoptotic apoptotic caspases chaperones chop cleaved context continuous cos7 cytoprotective decreasing ebp endoplasmic environments er homeostasis homologous inducer intra pro protection reticulum stress stresses thapsigargin triggers u0126 unfolded xl	appending competitively corepressor corest counteract demethylase demethylates demethylation derepression epigenetically erythro fates h3k4 lsd1 megakaryocytic nucleosomal opposes paralogs potentiate rcor rcor1 rcor2 rcor3 repressing restraining sant2 sharp upsurge
Tagcloud (Intersection) ?