NELL2

Name	neural EGFL like 2
Structure
Novel Interactors	1 novel interactors: BRD4
Interactors	9 interactors: ARX ATN1 ATXN7 CACNA1A DYRK1A GFI1B HOXA1 MBD1 PRKAR1A
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Protein Kinase C Binding Calcium Ion Binding Protein Binding Heparin Binding Identical Protein Binding
	Biological Process	Nervous System Development Fertilization Neuron Cellular Homeostasis Commissural Neuron Axon Guidance
Pathways	Regulation of commissural axon pathfinding by SLIT and ROBO
GWAS	Inflammatory bowel disease ( 27569725 ) Waist circumference ( 28552196 )
Entrez ID	4753
HPRD ID	11891
Ensembl ID	ENSG00000184613
Uniprot IDs	B7Z625 Q99435
PDB IDs	6POG
GO Terms Enriched among Interactors ?	Regulation Of Transcription By RNA Polymerase II Nuclear Matrix Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Transcription Coactivator Activity Regulation Of Metabolic Process Histone H3T45 Kinase Activity Semicircular Canal Formation Histone H4K8ac Reader Activity Negative Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Nucleus Positive Regulation Of Metabolic Process Chromatin Organization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Abducens Nerve Formation Optokinetic Behavior Histone H3K9ac Reader Activity Histone H4K5ac Reader Activity Histone H4K12ac Reader Activity Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Microtubule Polymerization Or Depolymerization DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of DNA Damage Checkpoint Histone H3K27ac Reader Activity Globus Pallidus Development Negative Regulation Of Metabolic Process P-TEFb Complex Binding Histone H4 Reader Activity Lipid Digestion Cerebral Cortex Tangential Migration Negative Regulation Of Heterochromatin Formation