NEK3 and BPGM

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		NEK3	BPGM
Gene Name		NIMA-related kinase 3	2,3-bisphosphoglycerate mutase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Axon	Extracellular Vesicular Exosome
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Bisphosphoglycerate Mutase Activity Bisphosphoglycerate 2-phosphatase Activity Phosphoglycerate Mutase Activity
	Biological Process	Protein Phosphorylation Mitotic Nuclear Division Cell Division	Carbohydrate Metabolic Process Glycolytic Process Respiratory Gaseous Exchange Dephosphorylation Erythrocyte Development
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: BPGM CDCA8 NMNAT1 PRLR VAV1 VAV2	9 interactors: AKT1 ATF6 ATP4B CEL EGR2 EHD2 GAPDH GRB2 NEK3
Entrez ID		4752	669
HPRD ID		04954	01961
Ensembl ID		ENSG00000136098	ENSG00000172331
Uniprot IDs		P51956 Q6ZN64	P07738
PDB IDs			1T8P 2A9J 2F90 2H4X 2H4Z 2H52 2HHJ 3NFY
Enriched GO Terms of Interacting Partners?		Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Body Fluid Levels Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Activation Of JAK2 Kinase Activity Immune System Process Prolactin Signaling Pathway Platelet Activation Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Positive Regulation Of Rho GTPase Activity Phagocytosis Activation Of Janus Kinase Activity Fc Receptor Signaling Pathway Regulation Of Rho GTPase Activity T Cell Aggregation Immune Response-activating Cell Surface Receptor Signaling Pathway T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Regulation Of Rho Protein Signal Transduction Apoptotic Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Apoptotic Process Prostate Gland Growth Lymphocyte Activation Fructose 2,6-bisphosphate Metabolic Process Blood Coagulation Positive Regulation Of Catalytic Activity Mammary Gland Epithelial Cell Differentiation Hemostasis Positive Regulation Of Ras GTPase Activity Regulation Of Cell Death Immune Response-regulating Signaling Pathway JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Leukocyte Activation Positive Regulation Of Kinase Activity Growth Hormone Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Cellular Response To Growth Hormone Stimulus Mitotic Metaphase Plate Congression NAD Biosynthetic Process	Regulation Of Body Fluid Levels Response To Organic Substance Response To Insulin Response To Organonitrogen Compound Labyrinthine Layer Development Schwann Cell Differentiation Cellular Response To Organic Substance T Cell Costimulation Rhombomere 5 Formation Rhombomere 3 Formation Glycogen Cell Differentiation Involved In Embryonic Placenta Development Peptidyl-cysteine S-trans-nitrosylation Protein Esterification Intestinal Lipid Catabolic Process Blood Coagulation Hemostasis Positive Regulation Of Reactive Oxygen Species Metabolic Process Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Peripheral Nervous System Development Rhombomere 3 Morphogenesis Embryonic Placenta Development Cellular Response To Hormone Stimulus Brain Segmentation Multicellular Organismal Lipid Catabolic Process Phosphatidylinositol-mediated Signaling Wound Healing Glucose Metabolic Process Myelination Axon Ensheathment Insulin Receptor Signaling Pathway Carbohydrate Biosynthetic Process Rhombomere 3 Development Rhombomere 5 Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Fatty Acid Beta-oxidation Regulation Of Reactive Oxygen Species Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Rhombomere Morphogenesis Peptidyl-cysteine S-nitrosylation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Response To Wounding Cellular Protein Metabolic Process Glial Cell Differentiation Response To UV-A Cellular Response To Fibroblast Growth Factor Stimulus
Tagcloud ?		abundantly attractive bodies cascades constructed determines eb ebs embryoid escs fragments govern hesm01 hesm02 huge igf1r keep kinases libraries mak makes mark3 nek7 northern pluripotency raf semi undifferentiated unlimited	biphosphoglycerate congenital csf3r epo epor erythrocytosis erythropoietin exhibit gelsolin germline haemoglobin hereditary inheritance inherited mendelian mpl mutase mutational myeloproliferative neutrophilia oxygen pedigrees sensing syndromes thpo thrombocytosis thrombopoietin uncovered v617f
Tagcloud (Difference) ?		abundantly attractive bodies cascades constructed determines eb ebs embryoid escs fragments govern hesm01 hesm02 huge igf1r keep kinases libraries mak makes mark3 nek7 northern pluripotency raf semi undifferentiated unlimited	biphosphoglycerate congenital csf3r epo epor erythrocytosis erythropoietin exhibit gelsolin germline haemoglobin hereditary inheritance inherited mendelian mpl mutase mutational myeloproliferative neutrophilia oxygen pedigrees sensing syndromes thpo thrombocytosis thrombopoietin uncovered v617f
Tagcloud (Intersection) ?