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MYBPC3 and TNNI3K
Number of citations of the paper that reports this interaction (PMID
12721663
)
9
Data Source:
HPRD
(two hybrid)
MYBPC3
TNNI3K
Gene Name
myosin binding protein C, cardiac
TNNI3 interacting kinase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytosol
Striated Muscle Myosin Thick Filament
C Zone
Sarcomere
A Band
Nucleus
Cytoplasm
Molecular Function
ATPase Activator Activity
Actin Binding
Structural Constituent Of Muscle
Myosin Binding
Titin Binding
Myosin Heavy Chain Binding
Identical Protein Binding
Metal Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Protein C-terminus Binding
Troponin I Binding
Metal Ion Binding
Biological Process
Regulation Of Heart Rate
Heart Morphogenesis
Regulation Of Striated Muscle Contraction
Cell Adhesion
Muscle Filament Sliding
Myosin Filament Assembly
Positive Regulation Of ATPase Activity
Regulation Of Muscle Filament Sliding
Sarcomere Organization
Ventricular Cardiac Muscle Tissue Morphogenesis
Cardiac Muscle Contraction
Protein Phosphorylation
Pathways
Striated Muscle Contraction
Drugs
Diseases
GWAS
Body mass index (
23669352
20935630
)
Obesity (
23563607
)
Pubertal anthropometrics (
23449627
)
Protein-Protein Interactions
7 interactors:
CAPN1
MYH9
NCF1
TNNI3K
TRIM55
TRIM63
TTN
7 interactors:
ACTA1
ACTC1
AIP
FABP3
HADHB
MYBPC3
TNNI3
Entrez ID
4607
51086
HPRD ID
02980
18208
Ensembl ID
ENSG00000134571
ENSG00000116783
Uniprot IDs
A5YM48
Q14896
Q59H18
PDB IDs
1GXE
1PD6
2AVG
2K1M
2V6H
3CX2
Enriched GO Terms of Interacting Partners
?
Actin Filament-based Movement
Actomyosin Structure Organization
Neutrophil Mediated Killing Of Gram-positive Bacterium
Neutrophil Mediated Killing Of Fungus
Sarcomerogenesis
Detection Of Muscle Stretch
Skeletal Muscle Myosin Thick Filament Assembly
Directional Locomotion
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Platelet Activation
Uropod Organization
Establishment Of Meiotic Spindle Localization
Myosin Filament Assembly
Establishment Of T Cell Polarity
Respiratory Burst Involved In Defense Response
Skeletal Muscle Atrophy
Response To Yeast
Muscle Contraction
Striated Muscle Cell Differentiation
Skeletal Muscle Thin Filament Assembly
Striated Muscle Atrophy
Muscle Atrophy
Killing By Host Of Symbiont Cells
Cardiac Muscle Fiber Development
Response To Muscle Stretch
Skeletal Myofibril Assembly
Muscle System Process
Skeletal Muscle Adaptation
Hydrogen Peroxide Biosynthetic Process
Meiotic Spindle Organization
Muscle Cell Differentiation
Respiratory Burst
Receptor Catabolic Process
Negative Regulation Of Smooth Muscle Contraction
Adult Heart Development
Superoxide Anion Generation
Monocyte Differentiation
Membrane Protein Ectodomain Proteolysis
Myoblast Fusion
Neutrophil Mediated Immunity
Blood Coagulation
Hemostasis
Negative Regulation Of Muscle Contraction
Platelet Formation
Platelet Morphogenesis
Cardiac Myofibril Assembly
Killing Of Cells Of Other Organism
Proteolysis
Cardiac Muscle Hypertrophy
Mitotic Chromosome Condensation
Actin-myosin Filament Sliding
Muscle Filament Sliding
Actin-mediated Cell Contraction
Actin Filament-based Movement
Muscle Contraction
Cardiac Muscle Contraction
Cardiac Muscle Tissue Morphogenesis
Muscle System Process
Muscle Tissue Morphogenesis
Muscle Organ Development
Heart Contraction
Muscle Organ Morphogenesis
Striated Muscle Tissue Development
Myofibril Assembly
Skeletal Muscle Thin Filament Assembly
Muscle Tissue Development
Striated Muscle Contraction
Skeletal Myofibril Assembly
Actomyosin Structure Organization
Muscle Structure Development
Striated Muscle Cell Development
Muscle Cell Development
Cardiac Muscle Tissue Development
Actin Filament-based Process
Heart Morphogenesis
Striated Muscle Cell Differentiation
Regulation Of ATPase Activity
Ventricular Cardiac Muscle Tissue Morphogenesis
Blood Circulation
Muscle Cell Differentiation
Ventricular Cardiac Muscle Tissue Development
Cardiac Ventricle Morphogenesis
Organelle Assembly
Heart Development
Cardiac Ventricle Development
Movement Of Cell Or Subcellular Component
Actin Cytoskeleton Organization
Skeletal Muscle Fiber Adaptation
Regulation Of Systemic Arterial Blood Pressure By Ischemic Conditions
Tissue Morphogenesis
Cardiac Chamber Development
Tissue Development
Regulation Of Muscle Contraction
Negative Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Regulation Of Muscle Filament Sliding
Myosin Filament Assembly
Cardiovascular System Development
Positive Regulation Of Phospholipid Biosynthetic Process
Cardiolipin Acyl-chain Remodeling
Long-chain Fatty Acid Import
Tagcloud
?
11p11
28x10
38x
73x10
a1
acp2
allele
attenuate
chr11
encompassing
epidemiology
fasting
fi
forkhead
foxa1
hepatoma
hg18
influencing
intron
jointly
kernel
lies
madd
nr1h3
rare
rs10838687
rs7944584
spi1
variants
Tagcloud (Difference)
?
11p11
28x10
38x
73x10
a1
acp2
allele
attenuate
chr11
encompassing
epidemiology
fasting
fi
forkhead
foxa1
hepatoma
hg18
influencing
intron
jointly
kernel
lies
madd
nr1h3
rare
rs10838687
rs7944584
spi1
variants
Tagcloud (Intersection)
?