MYBPC3

Gene Name		myosin binding protein C, cardiac
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Gene Ontology Annotations	Cellular Component	Cytosol Striated Muscle Myosin Thick Filament C Zone Sarcomere A Band
	Molecular Function	ATPase Activator Activity Actin Binding Structural Constituent Of Muscle Myosin Binding Titin Binding Myosin Heavy Chain Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Heart Rate Heart Morphogenesis Regulation Of Striated Muscle Contraction Cell Adhesion Muscle Filament Sliding Myosin Filament Assembly Positive Regulation Of ATPase Activity Regulation Of Muscle Filament Sliding Sarcomere Organization Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction
Pathways		Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: CAPN1 MYH9 NCF1 TNNI3K TRIM55 TRIM63 TTN
Entrez ID		4607
HPRD ID		02980
Ensembl ID		ENSG00000134571
Uniprot IDs		A5YM48 Q14896
PDB IDs		1GXE 1PD6 2AVG 2K1M 2V6H 3CX2
Enriched GO Terms of Interacting Partners?		Actin Filament-based Movement Actomyosin Structure Organization Neutrophil Mediated Killing Of Gram-positive Bacterium Neutrophil Mediated Killing Of Fungus Sarcomerogenesis Detection Of Muscle Stretch Skeletal Muscle Myosin Thick Filament Assembly Directional Locomotion Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation Platelet Activation Uropod Organization Establishment Of Meiotic Spindle Localization Myosin Filament Assembly Establishment Of T Cell Polarity Respiratory Burst Involved In Defense Response Skeletal Muscle Atrophy Response To Yeast Muscle Contraction Striated Muscle Cell Differentiation Skeletal Muscle Thin Filament Assembly Striated Muscle Atrophy Muscle Atrophy Killing By Host Of Symbiont Cells Cardiac Muscle Fiber Development Response To Muscle Stretch Skeletal Myofibril Assembly Muscle System Process Skeletal Muscle Adaptation Hydrogen Peroxide Biosynthetic Process Meiotic Spindle Organization Muscle Cell Differentiation Respiratory Burst Receptor Catabolic Process Negative Regulation Of Smooth Muscle Contraction Adult Heart Development Superoxide Anion Generation Monocyte Differentiation Membrane Protein Ectodomain Proteolysis Myoblast Fusion Neutrophil Mediated Immunity Blood Coagulation Hemostasis Negative Regulation Of Muscle Contraction Platelet Formation Platelet Morphogenesis Cardiac Myofibril Assembly Killing Of Cells Of Other Organism Proteolysis Cardiac Muscle Hypertrophy Mitotic Chromosome Condensation
Tagcloud ?		11p11 28x10 38x 73x10 a1 acp2 allele attenuate chr11 encompassing epidemiology fasting fi forkhead foxa1 hepatoma hg18 influencing intron jointly kernel lies madd nr1h3 rare rs10838687 rs7944584 spi1 variants