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MX2 and ATRIP
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
MX2
ATRIP
Gene Name
MX dynamin-like GTPase 2
ATR interacting protein
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nuclear Pore
Cytoplasm
Cytosol
Nucleus
Nucleoplasm
Molecular Function
GTPase Activity
GTP Binding
Protein Binding
K63-linked Polyubiquitin Binding
Biological Process
Defense Response
Metabolic Process
Response To Virus
Protein Transport
Cytokine-mediated Signaling Pathway
Response To Interferon-alpha
Regulation Of Nucleocytoplasmic Transport
MRNA Transport
Defense Response To Virus
Regulation Of Cell Cycle
Type I Interferon Signaling Pathway
DNA Damage Checkpoint
DNA Replication
DNA Repair
Pathways
ISG15 antiviral mechanism
Interferon Signaling
Cytokine Signaling in Immune system
Interferon alpha/beta signaling
Antiviral mechanism by IFN-stimulated genes
G2/M DNA damage checkpoint
G2/M Checkpoints
Activation of ATR in response to replication stress
Cell Cycle Checkpoints
Drugs
Diseases
GWAS
Melanoma (
21983787
)
Protein-Protein Interactions
3 interactors:
ATRIP
EHMT2
PIAS2
21 interactors:
ATR
BRCA1
C1orf94
CCDC28B
CDC23
CDC6
CDK16
CEP164
CINP
FAM156A
FAM208B
LNX1
METTL21A
MID2
MOS
MX2
POLR1C
PRKDC
RPA1
SCG2
SPRY2
Entrez ID
4600
84126
HPRD ID
01001
Ensembl ID
ENSG00000183486
ENSG00000164053
Uniprot IDs
P20592
Q8WXE1
PDB IDs
Enriched GO Terms of Interacting Partners
?
Peptidyl-lysine Modification
DNA Methylation On Cytosine Within A CG Sequence
Histone H3-K27 Methylation
Peptidyl-lysine Dimethylation
DNA Methylation On Cytosine
Negative Regulation Of Androgen Receptor Signaling Pathway
Regulation Of Androgen Receptor Signaling Pathway
Histone H3-K9 Methylation
Synaptonemal Complex Assembly
Synaptonemal Complex Organization
Protein Sumoylation
Histone H3-K9 Modification
Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Peptidyl-amino Acid Modification
Androgen Receptor Signaling Pathway
Cell Cycle Process
DNA Metabolic Process
Synapsis
Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Homologous Chromosome Segregation
Nucleobase-containing Compound Metabolic Process
DNA Methylation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Cell Cycle
Cellular Nitrogen Compound Metabolic Process
Cell Cycle
Cell Cycle Process
DNA Repair
Regulation Of Cell Cycle
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
DNA Metabolic Process
Cell Cycle Checkpoint
Cellular Response To DNA Damage Stimulus
DNA Replication
Organelle Organization
Response To Ionizing Radiation
Double-strand Break Repair
Negative Regulation Of DNA Replication
Mitotic Cell Cycle Process
Response To Gamma Radiation
Mitotic Cell Cycle
Negative Regulation Of Cell Cycle
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Cell Cycle Phase Transition
Regulation Of Cell Cycle Process
DNA Recombination
Cellular Protein Modification Process
Negative Regulation Of Protein Metabolic Process
Regulation Of Cell Division
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Cellular Protein Metabolic Process
Response To Stress
Negative Regulation Of DNA Metabolic Process
Cellular Response To Stress
Negative Regulation Of Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of DNA Replication
DNA Damage Checkpoint
Regulation Of Cellular Response To Heat
Cell Division
Response To Radiation
Positive Regulation Of Histone Methylation
Cellular Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Regulation Of Organelle Organization
Regulation Of Chromosome Organization
Cellular Metabolic Process
Establishment Of Spindle Orientation
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Mitotic Metaphase/anaphase Transition
Regulation Of Histone Methylation
Protein Ubiquitination
Chromosome Organization
Tagcloud
?
biochemically
canonical
checkpoint
checkpoints
concert
constitute
damage
damaged
enlargement
ercc1
excision
exo1
exonuclease
gap
integrity
mimetic
minimum
nucleotide
repair
rpa
steps
stranded
tfiih
topbp1
xpa
xpc
xpf
xpg
Tagcloud (Difference)
?
biochemically
canonical
checkpoint
checkpoints
concert
constitute
damage
damaged
enlargement
ercc1
excision
exo1
exonuclease
gap
integrity
mimetic
minimum
nucleotide
repair
rpa
steps
stranded
tfiih
topbp1
xpa
xpc
xpf
xpg
Tagcloud (Intersection)
?