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MX2

Name MX dynamin like GTPase 2
Structure PDB 4WHJ
Novel Interactors 6 novel interactors: IGFBP4 LSS MX1 NDUFV3 PKNOX1 STK38L
Interactors 3 interactors: ATRIP EHMT2 PIAS2
GO Annotations Cellular Component
  • Nucleus
  • Nuclear Envelope
  • Nuclear Pore
  • Cytoplasm
  • Cytosol
  • Microtubule
  • Plasma Membrane
  • Synapse
  • Presynapse
Molecular Function
  • Nucleotide Binding
  • GTPase Activity
  • Protein Binding
  • GTP Binding
  • Microtubule Binding
Biological Process
  • Immune System Process
  • Defense Response
  • Response To Virus
  • Protein Transport
  • Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane
  • Response To Interferon-alpha
  • Innate Immune Response
  • Regulation Of Nucleocytoplasmic Transport
  • MRNA Transport
  • Defense Response To Virus
  • Regulation Of Cell Cycle
Pathways
  • ISG15 antiviral mechanism
  • Interferon alpha/beta signaling
GWAS
  • Cutaneous malignant melanoma ( 32341527 )
  • Melanoma ( 21983787 28212542 )
  • Nevus count or cutaneous melanoma ( 30429480 32341527 )
  • Parkinson disease and lewy body pathology ( 25663231 )
  • Tau burden ( 33426524 )
Entrez ID 4600
HPRD ID 01001
Ensembl ID ENSG00000183486
Uniprot IDs P20592
PDB IDs 4WHJ 4X0R 5UOT

© Madhavi K. Ganapathiraju 2012-2026