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MMP1 and CMA1
Number of citations of the paper that reports this interaction (PubMedID
8027075
)
0
Data Source:
HPRD
(in vitro, in vivo)
MMP1
CMA1
Description
matrix metallopeptidase 1
chymase 1
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Matrix
Extracellular Region
Extracellular Space
Cytosol
Secretory Granule
Extracellular Matrix
Cytoplasmic Ribonucleoprotein Granule
Molecular Function
Endopeptidase Activity
Metalloendopeptidase Activity
Serine-type Endopeptidase Activity
Peptidase Activity
Metallopeptidase Activity
Zinc Ion Binding
Hydrolase Activity
Metal Ion Binding
Endopeptidase Activity
Serine-type Endopeptidase Activity
Peptidase Activity
Serine-type Peptidase Activity
Hydrolase Activity
Peptide Binding
Biological Process
Proteolysis
Extracellular Matrix Disassembly
Extracellular Matrix Organization
Collagen Catabolic Process
Positive Regulation Of Protein-containing Complex Assembly
Cellular Response To UV-A
Angiotensin Maturation
Proteolysis
Peptide Metabolic Process
Protein Processing
Extracellular Matrix Disassembly
Protein Catabolic Process
Midbrain Development
Basement Membrane Disassembly
Positive Regulation Of Angiogenesis
Regulation Of Inflammatory Response
Protein Maturation
Cellular Response To Glucose Stimulus
Cytokine Precursor Processing
Pathways
Collagen degradation
Collagen degradation
Degradation of the extracellular matrix
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Basigin interactions
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Interleukin-4 and Interleukin-13 signaling
Signaling by SCF-KIT
Activation of Matrix Metalloproteinases
Metabolism of Angiotensinogen to Angiotensins
Drugs
Marimastat
CGS-27023
N-[3-(N'-HYDROXYCARBOXAMIDO)-2-(2-METHYLPROPYL)-PROPANOYL]-O-TYROSINE-N-METHYLAMIDE
METHYLAMINO-PHENYLALANYL-LEUCYL-HYDROXAMIC ACID
[[1-[N-HYDROXY-ACETAMIDYL]-3-METHYL-BUTYL]-CARBONYL-LEUCINYL]-ALANINE ETHYL ESTER
N-HYDROXY-2-[4-(4-PHENOXY-BENZENESULFONYL)-TETRAHYDRO-PYRAN-4-YL]-ACETAMIDE
Benzylsulfonic acid
2-(N-morpholino)ethanesulfonic acid
2-[3-({Methyl[1-(2-Naphthoyl)Piperidin-4-Yl]Amino}Carbonyl)-2-Naphthyl]-1-(1-Naphthyl)-2-Oxoethylphosphonic Acid
[(1S)-1-(5-CHLORO-1-BENZOTHIEN-3-YL)-2-(2-NAPHTHYLAMINO)-2-OXOETHYL]PHOSPHONIC ACID
Diseases
Choriocarcinoma
GWAS
Blood protein levels (
30072576
)
Blood protein levels in cardiovascular risk (
28369058
)
Interacting Genes
17 interacting genes:
ACAN
BCAN
BSG
CCL13
CCL2
CCL7
CD44
CMA1
COL2A1
IGFBP3
ITGA2
MMP7
SERPINA3
SOX8
TFPI
TIMP1
TNFSF11
10 interacting genes:
AGT
EDN1
EDN2
EDN3
FYN
IL1B
KITLG
MMP1
PFN1
SERPINA3
Entrez ID
4312
1215
HPRD ID
00384
00346
Ensembl ID
ENSG00000196611
ENSG00000092009
Uniprot IDs
B4DN15
P03956
Q53G95
P23946
Q4FEB3
PDB IDs
1AYK
1CGE
1CGF
1CGL
1HFC
1SU3
2AYK
2CLT
2J0T
2TCL
3AYK
3SHI
4AUO
4AYK
966C
1KLT
1NN6
1PJP
1T31
2HVX
3N7O
3S0N
4AFQ
4AFS
4AFU
4AFZ
4AG1
4AG2
4K2Y
4K5Z
4K60
4K69
4KP0
5YJM
5YJP
7H60
7H61
7H62
7H63
7H64
7H65
7H66
7H67
7H68
7H69
7H6A
7H6B
7H6C
7H6D
7H6E
7H6F
7H6I
9GBH
9GC1
9GC9
9GCC
9GCD
Enriched GO Terms of Interacting Partners
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Extracellular Space
Extracellular Region
Extracellular Matrix
Myeloid Leukocyte Migration
Leukocyte Chemotaxis
Hyaluronic Acid Binding
Granulocyte Migration
Cell Chemotaxis
Regulation Of Cell Migration
Cell Migration
Granulocyte Chemotaxis
Cytokine Activity
Monocyte Chemotaxis
Eosinophil Migration
Eosinophil Chemotaxis
Regulation Of Cell Motility
Leukocyte Migration
CCR Chemokine Receptor Binding
Cell Motility
Regulation Of Locomotion
CCR2 Chemokine Receptor Binding
Animal Organ Morphogenesis
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Chemotaxis
Chemokine Activity
Positive Regulation Of Locomotion
Locomotion
Cytokine-mediated Signaling Pathway
Perineuronal Net
Chemokine-mediated Signaling Pathway
Regulation Of Cell Morphogenesis
Extracellular Matrix Organization
Extracellular Structure Organization
Cell Adhesion
Regulation Of Anatomical Structure Morphogenesis
Homeostatic Process
Inflammatory Response
Cartilage Development
Mononuclear Cell Migration
Peptidase Inhibitor Activity
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Regulation Of Apoptotic Process
Regulation Of Lymphocyte Chemotaxis
Anatomical Structure Morphogenesis
Cell Surface Receptor Signaling Pathway
Regulation Of Programmed Cell Death
Regulation Of Cell Shape
Positive Regulation Of Chemotaxis
Central Nervous System Development
Endothelin B Receptor Binding
Regulation Of Systemic Arterial Blood Pressure Mediated By A Chemical Signal
Vein Smooth Muscle Contraction
Leukocyte Migration
Vasoconstriction
Regulation Of Systemic Arterial Blood Pressure By Endothelin
Regulation Of Cell Migration
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Regulation Of Cell Motility
Positive Regulation Of Locomotion
Myeloid Leukocyte Migration
Regulation Of Systemic Arterial Blood Pressure
Regulation Of Locomotion
Positive Regulation Of Prostaglandin Biosynthetic Process
Artery Smooth Muscle Contraction
Neutrophil Chemotaxis
Tonic Smooth Muscle Contraction
Positive Regulation Of Unsaturated Fatty Acid Biosynthetic Process
Regulation Of Prostaglandin Biosynthetic Process
Regulation Of Vasoconstriction
Neutrophil Migration
Granulocyte Chemotaxis
Vascular Associated Smooth Muscle Contraction
Granulocyte Migration
Positive Regulation Of Fatty Acid Biosynthetic Process
Hormone Activity
Positive Regulation Of Heart Rate
Positive Regulation Of Cellular Component Organization
Circulatory System Process
Regulation Of Lipid Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Smooth Muscle Contraction
Positive Regulation Of Lipid Metabolic Process
Leukocyte Chemotaxis
Positive Regulation Of Leukocyte Migration
Positive Regulation Of Heart Contraction
Positive Regulation Of Fatty Acid Metabolic Process
Blood Vessel Diameter Maintenance
Regulation Of Tube Size
Positive Regulation Of Small Molecule Metabolic Process
Extracellular Region
Regulation Of Blood Pressure
Regulation Of Fatty Acid Biosynthetic Process
Positive Regulation Of Mitotic Nuclear Division
Axon Extension
Positive Regulation Of Muscle Contraction
System Process
Extracellular Space
Cell Migration
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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