CDH2 and BOC

Number of citations of the paper that reports this interaction (PMID 12634428)
25

Data Source:
HPRD (in vivo)

		CDH2	BOC
Gene Name		cadherin 2, type 1, N-cadherin (neuronal)	BOC cell adhesion associated, oncogene regulated
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Cell-cell Adherens Junction Fascia Adherens Focal Adhesion Intercalated Disc Integral Component Of Membrane Apical Plasma Membrane Catenin Complex Lamellipodium Synapse Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane Neuronal Cell Body Axonal Growth Cone
	Molecular Function	Calcium Ion Binding Protein Binding Beta-catenin Binding Protein Phosphatase Binding Alpha-catenin Binding Gamma-catenin Binding	Protein Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Glial Cell Differentiation Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Cell Junction Assembly Adherens Junction Organization Muscle Cell Differentiation Positive Regulation Of MAPK Cascade Cell-cell Adhesion Mediated By Cadherin Cell-cell Junction Organization Blood Vessel Morphogenesis Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Neuronal Stem Cell Maintenance	Cell Adhesion Smoothened Signaling Pathway Axon Guidance Muscle Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Muscle Cell Differentiation
Pathways		Cell junction organization Cell-cell junction organization CDO in myogenesis Myogenesis Adherens junctions interactions	Hedgehog 'on' state Signaling by Hedgehog Ligand-receptor interactions
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Temperament (bipolar disorder) ( 22365631) vWF and FVIII levels ( 21810271)	Dental caries ( 23259602) Prostate cancer ( 23535732)
Protein-Protein Interactions		22 interactors: ARHGAP32 ARVCF BOC CDH11 CDH4 CDON CREBBP CTNNA1 CTNNB1 CTNND2 EXOC5 FGFR4 GNA12 GNA13 GRIK2 GRIN1 GRIN2D JUP LRRC7 PIK3R1 PKP4 PTPN1	5 interactors: CDH15 CDH2 CDON CTNNB1 LRIF1
Entrez ID		1000	91653
HPRD ID		00226	12280
Ensembl ID		ENSG00000170558	ENSG00000144857
Uniprot IDs		A8MWK3 P19022	Q96DN7 Q9BWV1
PDB IDs			3N1G 3N1M 3N1P
Enriched GO Terms of Interacting Partners?		Cellular Response To Indole-3-methanol Adherens Junction Organization Cell Junction Assembly Cell-cell Junction Organization Cell Adhesion Regulation Of Signaling Cell Surface Receptor Signaling Pathway Signaling Cell Communication Signal Transduction Multicellular Organismal Development Regulation Of Signal Transduction Positive Regulation Of Muscle Cell Differentiation Anatomical Structure Morphogenesis Cellular Response To Organonitrogen Compound Regulation Of Cell Differentiation Single Organismal Cell-cell Adhesion Developmental Process Response To Organonitrogen Compound Cellular Response To Stimulus Cell Differentiation Anatomical Structure Development Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Muscle Cell Differentiation Response To Stimulus Regulation Of Cellular Component Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Glutamate Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Platelet Activation Neuron-neuron Synaptic Transmission Embryonic Digit Morphogenesis Regulation Of Cell Morphogenesis Regulation Of Neural Precursor Cell Proliferation Locomotion Regulation Of Intracellular Signal Transduction Epithelial Cell-cell Adhesion Cell-cell Junction Assembly Enzyme Linked Receptor Protein Signaling Pathway Axon Development Cell-cell Signaling Vascular Endothelial Growth Factor Receptor Signaling Pathway Homeostatic Process Cellular Component Assembly Protein Heterooligomerization Regulation Of Cell Fate Specification Cellular Response To Peptide Hormone Stimulus Muscle Cell Differentiation Regulation Of MAPK Cascade	Positive Regulation Of Muscle Cell Differentiation Regulation Of Muscle Cell Differentiation Muscle Cell Differentiation Adherens Junction Organization Muscle Structure Development Cell Junction Assembly Cell-cell Junction Organization Positive Regulation Of Cell Differentiation Cell Adhesion Positive Regulation Of Neural Precursor Cell Proliferation Positive Regulation Of MAPK Cascade Regulation Of Cell Differentiation Cell Fate Specification Lens Development In Camera-type Eye Regulation Of MAPK Cascade Regulation Of Neural Precursor Cell Proliferation Camera-type Eye Morphogenesis Positive Regulation Of Intracellular Signal Transduction Stem Cell Maintenance Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Cerebral Cortex Development Eye Morphogenesis Positive Regulation Of Phosphorylation Glial Cell Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion Cell-cell Adhesion Mediated By Cadherin Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Pallium Development Positive Regulation Of Determination Of Dorsal Identity Skeletal Muscle Satellite Cell Differentiation Lung Induction Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Regulation Of Canonical Wnt Signaling Pathway Striated Muscle Cell Differentiation Central Nervous System Vasculogenesis Trachea Formation Cellular Response To Indole-3-methanol Gliogenesis
Tagcloud ?		bioinformatics blotting cadherin downregulating embedded expressions fixed formalin igf1r immunohistochemistry lentiviruses luciferase metastasis mir os osteosarcoma paraffin paraformalin partially predicted probably promising prove quantitative real reporter sosp transfected u2	asp caspase cd95 cho converting deltapsim devd disruption dp equivalents externalization fas fmk intermediates jurkat pentose phosphatidylserine ppp preceded proteases proteolysis ps ribose roi sequelae supply tal transaldolase vad
Tagcloud (Difference) ?		bioinformatics blotting cadherin downregulating embedded expressions fixed formalin igf1r immunohistochemistry lentiviruses luciferase metastasis mir os osteosarcoma paraffin paraformalin partially predicted probably promising prove quantitative real reporter sosp transfected u2	asp caspase cd95 cho converting deltapsim devd disruption dp equivalents externalization fas fmk intermediates jurkat pentose phosphatidylserine ppp preceded proteases proteolysis ps ribose roi sequelae supply tal transaldolase vad
Tagcloud (Intersection) ?