CDH2 and CDH4

Number of citations of the paper that reports this interaction (PMID 10662782)
30

Data Source:
HPRD (in vivo)

		CDH2	CDH4
Gene Name		cadherin 2, type 1, N-cadherin (neuronal)	cadherin 4, type 1, R-cadherin (retinal)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Cell-cell Junction Cell-cell Adherens Junction Fascia Adherens Focal Adhesion Intercalated Disc Integral Component Of Membrane Apical Plasma Membrane Catenin Complex Lamellipodium Synapse Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Beta-catenin Binding Protein Phosphatase Binding Alpha-catenin Binding Gamma-catenin Binding	Calcium Ion Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Glial Cell Differentiation Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Cell Migration Cell Junction Assembly Adherens Junction Organization Muscle Cell Differentiation Positive Regulation Of MAPK Cascade Cell-cell Adhesion Mediated By Cadherin Cell-cell Junction Organization Blood Vessel Morphogenesis Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Negative Regulation Of Canonical Wnt Signaling Pathway Neuronal Stem Cell Maintenance	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Axon Guidance Cell Junction Assembly Adherens Junction Organization Cell-cell Junction Organization Positive Regulation Of Axon Extension
Pathways		Cell junction organization Cell-cell junction organization CDO in myogenesis Myogenesis Adherens junctions interactions	Cell junction organization Cell-cell junction organization CDO in myogenesis Myogenesis Adherens junctions interactions
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Temperament (bipolar disorder) ( 22365631) vWF and FVIII levels ( 21810271)	β2-Glycoprotein I (β2-GPI) plasma levels ( 23279374) Longevity ( 20834067) Obesity-related traits ( 23251661) Sudden cardiac arrest ( 21658281) T-tau ( 20932310) Volumetric brain MRI ( 17903297)
Protein-Protein Interactions		22 interactors: ARHGAP32 ARVCF BOC CDH11 CDH4 CDON CREBBP CTNNA1 CTNNB1 CTNND2 EXOC5 FGFR4 GNA12 GNA13 GRIK2 GRIN1 GRIN2D JUP LRRC7 PIK3R1 PKP4 PTPN1	1 interactors: CDH2
Entrez ID		1000	1002
HPRD ID		00226	04304
Ensembl ID		ENSG00000170558	ENSG00000179242
Uniprot IDs		A8MWK3 P19022	P55283
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Indole-3-methanol Adherens Junction Organization Cell Junction Assembly Cell-cell Junction Organization Cell Adhesion Regulation Of Signaling Cell Surface Receptor Signaling Pathway Signaling Cell Communication Signal Transduction Multicellular Organismal Development Regulation Of Signal Transduction Positive Regulation Of Muscle Cell Differentiation Anatomical Structure Morphogenesis Cellular Response To Organonitrogen Compound Regulation Of Cell Differentiation Single Organismal Cell-cell Adhesion Developmental Process Response To Organonitrogen Compound Cellular Response To Stimulus Cell Differentiation Anatomical Structure Development Ionotropic Glutamate Receptor Signaling Pathway Synaptic Transmission, Glutamatergic Regulation Of Muscle Cell Differentiation Response To Stimulus Regulation Of Cellular Component Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Glutamate Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Platelet Activation Neuron-neuron Synaptic Transmission Embryonic Digit Morphogenesis Regulation Of Cell Morphogenesis Regulation Of Neural Precursor Cell Proliferation Locomotion Regulation Of Intracellular Signal Transduction Epithelial Cell-cell Adhesion Cell-cell Junction Assembly Enzyme Linked Receptor Protein Signaling Pathway Axon Development Cell-cell Signaling Vascular Endothelial Growth Factor Receptor Signaling Pathway Homeostatic Process Cellular Component Assembly Protein Heterooligomerization Regulation Of Cell Fate Specification Cellular Response To Peptide Hormone Stimulus Muscle Cell Differentiation Regulation Of MAPK Cascade	Cell-cell Adhesion Mediated By Cadherin Neuronal Stem Cell Maintenance Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Positive Regulation Of Muscle Cell Differentiation Adherens Junction Organization Negative Regulation Of Canonical Wnt Signaling Pathway Stem Cell Maintenance Regulation Of Muscle Cell Differentiation Glial Cell Differentiation Negative Regulation Of Wnt Signaling Pathway Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell Junction Assembly Cell-cell Junction Organization Regulation Of Canonical Wnt Signaling Pathway Striated Muscle Cell Differentiation Gliogenesis Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Stem Cell Development Regulation Of Wnt Signaling Pathway Stem Cell Differentiation Muscle Cell Differentiation
Tagcloud ?		bioinformatics blotting cadherin downregulating embedded expressions fixed formalin igf1r immunohistochemistry lentiviruses luciferase metastasis mir os osteosarcoma paraffin paraformalin partially predicted probably promising prove quantitative real reporter sosp transfected u2
Tagcloud (Difference) ?		bioinformatics blotting cadherin downregulating embedded expressions fixed formalin igf1r immunohistochemistry lentiviruses luciferase metastasis mir os osteosarcoma paraffin paraformalin partially predicted probably promising prove quantitative real reporter sosp transfected u2
Tagcloud (Intersection) ?