SMAD4 and GLI3

  • Number of citations of the paper that reports this interaction (PMID 9843199)
  • 20
  • Data Source:
  • HPRD (in vitro)

SMAD4

GLI3

Gene Name SMAD family member 4 GLI family zinc finger 3
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Immune response to anthrax vaccine ( 22658931)
Protein-Protein Interactions 174 interactors: ACVR1B AKT1 AP2B1 APBB2 AR ARFRP1 ARL5B ATF2 ATF7IP BRCA1 BTRC CAMK2G CD59 CEBPA CEBPB CEBPD CHEK1 CITED1 CNKSR1 COPS5 CREBBP CSH1 CSH2 CTCF CTNNB1 CYFIP2 DACH1 DCP1A DCP1B DLX1 DNAJB2 DVL1 ECSIT EEF1A1 EID2 EIF2AK4 EP300 ERBB2IP ESR1 ESR2 EWSR1 FBLN1 FBXO30 FBXO34 FHL2 FHL3 FN1 FOXG1 FOXH1 FOXO1 FOXO3 FOXO4 FSTL3 GATA2 GLI3 GPNMB HDGF HDLBP HMG20A HNF4A HOXA9 HOXC8 ITK JUN JUNB JUND LEF1 LMO4 MAPK1 MAPK13 MAX MDM4 MECOM MEF2A MEX3B MYOD1 NAT8 NEK6 NELFCD NF1 NKX3-2 NOTCH4 NR0B2 NRAS NUAK2 NUP214 OTUB1 PAK1 PAPPA2 PARD3 PARD3B PBK PIAS1 PIAS2 PIAS3 PIAS4 PLG PLK4 PRKAR1B PRKAR2A PRPF40A PSG2 PSG9 PSMD11 RAB13 RAB25 RAB2B RAB34 RAB38 RAB3B RAC2 RALA RASD2 RASL12 RASSF5 RBL1 RELA RFX1 RHEBL1 RHOD RHOG RHOJ RIPK2 RMND5B RPL28 RPS27A RRAS2 RSPH14 SASH3 SERPINA1 SKI SKIL SKP2 SMAD1 SMAD2 SMAD3 SMAD5 SMAD7 SMAD9 SNIP1 SNRNP70 SNW1 SOX12 SP1 SPTBN1 SQSTM1 STK11IP STK35 STUB1 TCTA TDG TENM3 TFE3 TGFBR1 TGFBR2 TGFBRAP1 TM9SF2 TOB1 TRAP1 TSSK3 UBA52 UBB UBE2I UBE2L3 UBE2Z UHRF2 USB1 USP9X XPO5 ZBED5 ZMYM2 ZNF423 ZNF521 ZNF8 17 interactors: BTRC CREBBP CSNK1A1 GSK3A MED12 PRKCA SKI SMAD1 SMAD2 SMAD3 SMAD4 STK36 SUFU TWIST1 ZIC1 ZIC2 ZIC3
Entrez ID 4089 2737
HPRD ID 02995 01313
Ensembl ID ENSG00000141646 ENSG00000106571
Uniprot IDs Q13485 P10071
PDB IDs 1DD1 1G88 1MR1 1U7F 1U7V 1YGS
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adenoviral  autoinhibitory  cdk  coactivators  competing  conformational  constructs  creb  define  e1a  effector  facilitating  fragment  interacting  modulates  oncoprotein  p15  p300  participate  possibility  potentiates  removes  smad3  smads  squelching  tgf  transactivation  transduce 
act  antitumor  application  blocks  cancers  combined  component  could  cyclopamine  directions  downstream  enhance  glioma  gynecological  hedgehog  induce  leading  malignancy  management  mortality  oncogene  ovarian  pathway  proliferation  reduce  signaling  silencing  therefore 
Tagcloud (Difference) ?
adenoviral  autoinhibitory  cdk  coactivators  competing  conformational  constructs  creb  define  e1a  effector  facilitating  fragment  interacting  modulates  oncoprotein  p15  p300  participate  possibility  potentiates  removes  smad3  smads  squelching  tgf  transactivation  transduce 
act  antitumor  application  blocks  cancers  combined  component  could  cyclopamine  directions  downstream  enhance  glioma  gynecological  hedgehog  induce  leading  malignancy  management  mortality  oncogene  ovarian  pathway  proliferation  reduce  signaling  silencing  therefore 
Tagcloud (Intersection) ?