MIR29C and DZIP3

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR29C	DZIP3
Description		microRNA 29c	DAZ interacting zinc finger protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion RISC Complex Extracellular Exosome Extracellular Vesicle	Cytoplasm
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Transferase Activity Phosphatase Binding Polyubiquitin Modification-dependent Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Epigenetic Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Circulating Fibrinogen Levels Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Protein Polyubiquitination Protein Ubiquitination
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 27863252)
Interacting Genes		87 interacting genes: ADARB1 AIMP1 APOBEC3B C1QBP CELF1 CELF2 CPSF7 DARS1 DDX1 DDX21 DDX3X DHX36 DZIP3 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ STRBP SUGP2 SYNCRIP TAF15 TENT2 TIAL1 TRA2A TRA2B U2SURP UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	53 interacting genes: AKTIP AP1M1 ARHGAP32 ATXN1 BAG4 BIRC2 BIRC3 CARM1 CCND1 CEP63 DAZ1 FBXO17 GRIP1 GTF2H2C_2 HNRNPF HNRNPH1 HNRNPUL1 HOTAIR HOXC8 MIR20A MIR29C NCOR1 PCGF3 PITX1 RAD18 RBM4B RNF38 RUNX1 TNS2 TOLLIP TRIM21 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2I UBE2K UBE2N UBE2R2 UBE2U UBE2V1 UBE2V2 UBE2W UBE2Z UBR3 ZCCHC10 ZNF24 ZNF765
Entrez ID		407026	9666
HPRD ID			10562
Ensembl ID		ENSG00000284214	ENSG00000198919
Uniprot IDs			Q86Y13
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process MRNA Binding Nucleobase-containing Compound Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Nucleus Macromolecule Metabolic Process Post-transcriptional Regulation Of Gene Expression Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of Translation MRNA 3'-UTR Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Spliceosomal Complex Catalytic Step 2 Spliceosome Negative Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Negative Regulation Of RNA Catabolic Process Regulation Of Primary Metabolic Process MiRNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of MRNA Stability TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Metabolic Process TRNA Aminoacylation MRNA Stabilization Regulation Of RNA Stability Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation	Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-protein Transferase Activity Post-translational Protein Modification Proteolysis Involved In Protein Catabolic Process Protein K48-linked Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Monoubiquitination Macromolecule Catabolic Process Protein Modification Process Protein K63-linked Ubiquitination Proteolysis Regulation Of Protein Polyubiquitination Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Polyubiquitination Protein K11-linked Ubiquitination Transferase Activity Protein Metabolic Process Positive Regulation Of Protein K63-linked Ubiquitination Macromolecule Metabolic Process UBC13-MMS2 Complex Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Post-translational Protein Modification Regulation Of Protein Modification Process Regulation Of Protein Metabolic Process Postreplication Repair Ubiquitin Conjugating Enzyme Complex Ubiquitin Protein Ligase Activity Nucleus Positive Regulation Of Post-translational Protein Modification Proteasomal Protein Catabolic Process Positive Regulation Of Protein Modification Process Regulation Of Metabolic Process Catabolic Process Nucleoplasm Positive Regulation Of Protein Ubiquitination Regulation Of Protein Ubiquitination Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process ATP Binding DNA Damage Response Positive Regulation Of Protein Metabolic Process Error-free Postreplication DNA Repair Negative Regulation Of Macromolecule Metabolic Process DNA Repair Regulation Of RNA Metabolic Process
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