MIR29C and USP36

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR29C	USP36
Description		microRNA 29c	ubiquitin specific peptidase 36
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion RISC Complex Extracellular Exosome Extracellular Vesicle	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Nuclear Speck
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	RNA Binding Cysteine-type Deubiquitinase Activity Protein Binding Peptidase Activity Cysteine-type Peptidase Activity Transferase Activity Hydrolase Activity Histone H2B Deubiquitinase Activity K48-linked Deubiquitinase Activity
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Epigenetic Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Circulating Fibrinogen Levels Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Chromatin Organization Chromatin Remodeling Proteolysis Nucleolus Organization Negative Regulation Of Macroautophagy Protein Deubiquitination Regulation Of Protein Stability Regulation Of Apoptotic Process Protein Stabilization Regulation Of Mitophagy Positive Regulation Of Protein Targeting To Mitochondrion Regulation Of RRNA Processing
Pathways
Drugs
Diseases
GWAS			Atrial fibrillation ( 30061737) Diverticular disease ( 30177863) Heel bone mineral density ( 30598549) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 30578418 31928498)
Interacting Genes		87 interacting genes: ADARB1 AIMP1 APOBEC3B C1QBP CELF1 CELF2 CPSF7 DARS1 DDX1 DDX21 DDX3X DHX36 DZIP3 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ STRBP SUGP2 SYNCRIP TAF15 TENT2 TIAL1 TRA2A TRA2B U2SURP UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	19 interacting genes: ALKBH5 EXOSC10 H2BC3 MIR128-1 MIR138-2 MIR15B MIR16-1 MIR17 MIR19B2 MIR21 MIR29A MIR29C MIR34B MIR7-1 MYC PRIMPOL PTBP1 SUMO2 UBE2I
Entrez ID		407026	57602
HPRD ID			07164
Ensembl ID		ENSG00000284214	ENSG00000055483
Uniprot IDs			A0A075B784 Q9P275
PDB IDs			8BS3 8BS9
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process MRNA Binding Nucleobase-containing Compound Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Nucleus Macromolecule Metabolic Process Post-transcriptional Regulation Of Gene Expression Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of Translation MRNA 3'-UTR Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Spliceosomal Complex Catalytic Step 2 Spliceosome Negative Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Negative Regulation Of RNA Catabolic Process Regulation Of Primary Metabolic Process MiRNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of MRNA Stability TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Metabolic Process TRNA Aminoacylation MRNA Stabilization Regulation Of RNA Stability Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation	MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing Negative Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process MRNA 3'-UTR Binding Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Translation Negative Regulation Of Metabolic Process Negative Regulation Of Vasculature Development Negative Regulation Of Angiogenesis Regulation Of Translation Positive Regulation Of Connective Tissue Replacement Extracellular Vesicle Regulation Of Connective Tissue Replacement Regulation Of Gene Expression Positive Regulation Of Tissue Remodeling Regulation Of Macromolecule Biosynthetic Process Regulation Of Endothelial Cell Proliferation Negative Regulation Of Amyloid-beta Formation Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Developmental Process Regulation Of Amide Metabolic Process Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of Vascular Endothelial Cell Proliferation Regulation Of Macromolecule Metabolic Process Regulation Of Epithelial Cell Proliferation Negative Regulation Of Protein Metabolic Process Regulation Of Amyloid-beta Formation Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Endothelial Cell Proliferation Regulation Of Metabolic Process Negative Regulation Of Vascular Endothelial Growth Factor Production Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Intracellular Signal Transduction Negative Regulation Of Endothelial Cell Migration Negative Regulation Of Cell Migration Positive Regulation Of Apoptotic Process Regulation Of Cell Cycle G1/S Phase Transition
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