MIR29C and CELF2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		MIR29C	CELF2
Description		microRNA 29c	CUGBP Elav-like family member 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion RISC Complex Extracellular Exosome Extracellular Vesicle	Nucleus Nucleoplasm Cytoplasm Flemming Body Ribonucleoprotein Complex
	Molecular Function	MRNA 3'-UTR Binding MRNA Base-pairing Post-transcriptional Repressor Activity	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Pre-mRNA Binding
	Biological Process	Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Extracellular Matrix Disassembly Negative Regulation Of Angiogenesis Negative Regulation Of Cell Migration MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By Inhibition Of Translation Epigenetic Regulation Of Gene Expression Positive Regulation Of Apoptotic Process Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Circulating Fibrinogen Levels Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Negative Regulation Of Amyloid-beta Formation Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Negative Regulation Of Vascular Endothelial Cell Proliferation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splice Site Recognition RNA Processing MRNA Processing Regulation Of Heart Contraction
Pathways
Drugs
Diseases
GWAS			Activity variability during wake ( 33075057) Adult body size ( 32376654) Adventurousness ( 30643258) Adverse response to drug ( 30420678) Age at first sexual intercourse ( 34211149) Allergic rhinitis ( 30013184) Asthma ( 29273806 34103634) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Basal cell carcinoma ( 33549134) Body size at age 10 ( 32376654) Breastfeeding duration ( 25475840) Chronic kidney disease ( 31015462) Cognitive function in longevity ( 33607172) General risk tolerance (MTAG) ( 30643258) Glaucoma (primary open-angle) ( 33627673) Glycemic traits (pleiotropy) ( 31021400) Liver enzyme levels (alanine transaminase) ( 24124411) Liver enzyme levels (aspartate transaminase) ( 24124411) Mean platelet volume ( 32888494) Motion sickness ( 25628336) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 30224653) Response to lamotrigine in genetic generalized epilepsy ( 32308125) Urinary albumin-to-creatinine ratio ( 26631737)
Interacting Genes		87 interacting genes: ADARB1 AIMP1 APOBEC3B C1QBP CELF1 CELF2 CPSF7 DARS1 DDX1 DDX21 DDX3X DHX36 DZIP3 EDC4 EIF2AK2 EPRS1 ESRP1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LARS1 LIN28A LRPPRC MARS1 MATR3 MSI1 MSI2 MYEF2 NOL6 NONO NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUF60 PUM1 PURA PURB QARS1 RARS1 RBFOX2 RBM14 RBM4 RTCA RTCB SF3A1 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ STRBP SUGP2 SYNCRIP TAF15 TENT2 TIAL1 TRA2A TRA2B U2SURP UPF1 USP36 UTP20 YBX1 YBX2 YBX3 ZFR ZNF346	23 interacting genes: A1CF APOBEC1 APP CEBPA ELAVL1 MIR140 MIR155 MIR18B MIR199A1 MIR19A MIR19B1 MIR205 MIR21 MIR29C MIR34B MIR363 MIR7-1 MIR9-2 MIRLET7I PCBP1 PTGS2 RNF10 TRAF3
Entrez ID		407026	10659
HPRD ID			03964
Ensembl ID		ENSG00000284214	ENSG00000048740
Uniprot IDs			A0A0J9YX66 A0A0J9YXJ0 A0A1B0GU44 A0A1B0GUN8 B4DDE7 B4DIB6 B4DT00 B4DZ01 E9PC62 O95319
PDB IDs			2MY7 2MY8 4LJM 4LMZ 4TLQ 5M8I
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing MRNA Processing Nucleic Acid Metabolic Process MRNA Metabolic Process MRNA Binding Nucleobase-containing Compound Metabolic Process Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process Nucleus Macromolecule Metabolic Process Post-transcriptional Regulation Of Gene Expression Nucleoplasm MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Aminoacyl-tRNA Synthetase Multienzyme Complex Regulation Of Translation MRNA 3'-UTR Binding Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Cytoplasmic Stress Granule Spliceosomal Complex Catalytic Step 2 Spliceosome Negative Regulation Of MRNA Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Translation Negative Regulation Of RNA Catabolic Process Regulation Of Primary Metabolic Process MiRNA Binding Regulation Of Macromolecule Metabolic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Catabolic Process RNA Stabilization Regulation Of MRNA Stability TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Metabolic Process TRNA Aminoacylation MRNA Stabilization Regulation Of RNA Stability Negative Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Pre-mRNA Binding Positive Regulation Of Cytoplasmic Translation	Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression RISC Complex MRNA 3'-UTR Binding Negative Regulation Of Gene Expression Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Cardiac Muscle Hypertrophy Negative Regulation Of Multicellular Organismal Process MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Developmental Process Regulation Of Extracellular Matrix Organization Negative Regulation Of Endothelial Cell Migration Regulation Of Cardiac Muscle Hypertrophy Regulation Of Defense Response Regulation Of Inflammatory Response Regulation Of Cytokine Production Regulation Of Multicellular Organismal Process Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Matrix Metallopeptidase Secretion Positive Regulation Of Muscle Cell Differentiation Positive Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Extracellular Vesicle Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cell Differentiation Negative Regulation Of Striated Muscle Cell Apoptotic Process Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability MRNA Destabilization Negative Regulation Of Cell Migration Regulation Of Endothelial Cell Migration MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Cell Population Proliferation RNA Destabilization Negative Regulation Of Cytokine Production Negative Regulation Of Cell Motility Regulation Of RNA Stability Regulation Of Developmental Process Regulation Of Cell Population Proliferation
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