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LGALS2 and TUBA4A
Number of citations of the paper that reports this interaction (PMID
15129282
)
36
Data Source:
HPRD
(in vivo)
LGALS2
TUBA4A
Gene Name
lectin, galactoside-binding, soluble, 2
tubulin, alpha 4a
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Region
Cytosol
Microtubule
Extracellular Vesicular Exosome
Molecular Function
Galactoside Binding
Carbohydrate Binding
GTPase Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Platelet Degranulation
Protein Folding
Organelle Organization
Microtubule-based Process
Blood Coagulation
Platelet Activation
Cellular Protein Metabolic Process
'de Novo' Posttranslational Protein Folding
Protein Polymerization
Pathways
Transport of connexons to the plasma membrane
Hedgehog 'off' state
Platelet degranulation
Formation of tubulin folding intermediates by CCT/TriC
Regulation of PLK1 Activity at G2/M Transition
Prefoldin mediated transfer of substrate to CCT/TriC
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
Gap junction trafficking and regulation
Response to elevated platelet cytosolic Ca2+
Recruitment of mitotic centrosome proteins and complexes
Gap junction assembly
Gap junction trafficking
Factors involved in megakaryocyte development and platelet production
Resolution of Sister Chromatid Cohesion
Platelet activation, signaling and aggregation
Mitotic G2-G2/M phases
Mitotic Metaphase and Anaphase
Adaptive Immune System
Mitotic Prometaphase
Organelle biogenesis and maintenance
Axon guidance
Separation of Sister Chromatids
Translocation of GLUT4 to the plasma membrane
G2/M Transition
L1CAM interactions
Mitotic Anaphase
Recycling pathway of L1
Recruitment of NuMA to mitotic centrosomes
M Phase
Intraflagellar transport
Post-chaperonin tubulin folding pathway
Loss of Nlp from mitotic centrosomes
MHC class II antigen presentation
Protein folding
Kinesins
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Assembly of the primary cilium
Anchoring of the basal body to the plasma membrane
Cell Cycle, Mitotic
Loss of proteins required for interphase microtubule organization from the centrosome
Signaling by Hedgehog
Chaperonin-mediated protein folding
Centrosome maturation
Drugs
Vincristine
Podofilox
Epothilone D
Epothilone B
Cabazitaxel
Diseases
GWAS
Response to antidepressant treatment (
22041458
)
Protein-Protein Interactions
6 interactors:
APP
IKBKG
LTA
SDCBP
SDCBP2
TUBA4A
49 interactors:
APC
ARHGAP1
B4GALT1
BCAR1
BRCA1
C4orf17
CALB2
EGFR
ENO2
EPB41
FYN
GNAI2
GPHN
GRM7
HDAC6
HSPH1
LGALS2
LTA
MAGED1
MAP1A
MAP1LC3A
MAPT
MARK4
MYC
NCALD
PARK2
PFDN4
PLK1
RAB8B
RAC1
RACGAP1
RBM23
RTN4
S100A8
SIAH1
SIMC1
SIRT2
STARD13
SYK
TAOK2
TBCB
TBCE
TCP1
TM4SF1
UCHL5
VAV1
VDAC1
YWHAG
ZAP70
Entrez ID
3957
7277
HPRD ID
08859
01851
Ensembl ID
ENSG00000100079
ENSG00000127824
Uniprot IDs
P05162
A8MUB1
P68366
PDB IDs
1HLC
Enriched GO Terms of Interacting Partners
?
Establishment Of Localization In Cell
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Cellular Localization
Platelet Degranulation
Response To External Stimulus
Cellular Response To Stimulus
Synaptic Growth At Neuromuscular Junction
Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus
Collateral Sprouting In Absence Of Injury
Positive Regulation Of Extracellular Vesicular Exosome Assembly
Platelet Activation
Intracellular Receptor Signaling Pathway
Nervous System Development
Collateral Sprouting
Axon Midline Choice Point Recognition
Apoptotic Process
Programmed Cell Death
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Regulation Of Extracellular Vesicular Exosome Assembly
Cell Death
Death
Axon Choice Point Recognition
Positive Regulation Of Chronic Inflammatory Response
Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin
Response To Stimulus
Neuron Remodeling
Signal Transduction
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Immune Response
Regulation Of Phosphorylation
Exocytosis
Substrate-dependent Cell Migration, Cell Extension
Defense Response
Positive Regulation Of Inflammatory Response To Antigenic Stimulus
Positive Regulation Of Cytokine Production
Regulation Of Chronic Inflammatory Response
Signaling
Positive Regulation Of Glial Cell Proliferation
Axon Guidance
Cell Communication
Regulation Of Phosphorus Metabolic Process
Lymph Node Development
Positive Regulation Of Humoral Immune Response
Blood Coagulation
Intracellular Transport
Cellular Copper Ion Homeostasis
Hemostasis
Generation Of Neurons
Positive Regulation Of MAPK Cascade
Regulation Of Cell Death
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Apoptotic Process
Response To Stress
Programmed Cell Death
Cell Death
Death
Positive Regulation Of Apoptotic Process
Regulation Of Signaling
Apoptotic Process
Cell Migration
Cell Communication
Regulation Of Cellular Component Organization
Positive Regulation Of Signal Transduction
Response To Stimulus
Regulation Of Signal Transduction
Cell Motility
Regulation Of Intracellular Signal Transduction
Response To Growth Factor
Regulation Of Reactive Oxygen Species Metabolic Process
Cellular Response To Stimulus
Intracellular Signal Transduction
Regulation Of Catalytic Activity
Locomotion
Movement Of Cell Or Subcellular Component
Response To Organic Substance
Signaling
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Organelle Organization
'de Novo' Posttranslational Protein Folding
Cellular Response To Growth Factor Stimulus
'de Novo' Protein Folding
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Protein Metabolic Process
Neurotrophin Signaling Pathway
Positive Regulation Of Intracellular Signal Transduction
Leukocyte Migration
Signal Transduction
Positive Regulation Of Protein Metabolic Process
Regulation Of Cellular Localization
Regulation Of Cytoskeleton Organization
Regulation Of Cellular Protein Metabolic Process
Organelle Organization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Nervous System Development
Regulation Of Microtubule-based Process
Positive Regulation Of Organelle Organization
Positive Regulation Of Cellular Protein Metabolic Process
Tagcloud
?
34x10
abl1
applying
await
biology
fyn
gwas
hypothesised
illustrates
inpp5d
interactome
interactomes
interactor
interactors
kif1b
loci
pairwise
phenotypes
pik3r1
plcg1
prioritisation
prioritization
prkcd
shared
trait
ubc
unpredictable
unravel
Tagcloud (Difference)
?
34x10
abl1
applying
await
biology
fyn
gwas
hypothesised
illustrates
inpp5d
interactome
interactomes
interactor
interactors
kif1b
loci
pairwise
phenotypes
pik3r1
plcg1
prioritisation
prioritization
prkcd
shared
trait
ubc
unpredictable
unravel
Tagcloud (Intersection)
?