LGALS2

Description		galectin 2
Image
GO Annotations	Cellular Component	Galectin Complex
	Molecular Function	Protein Binding Galactoside Binding Carbohydrate Binding
	Biological Process	T Cell Homeostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Inflammatory Response Cell-cell Adhesion
Pathways
Drugs		Beta-D-Glucose
Diseases
GWAS		Blood protein levels ( 30072576) Response to anti-depressant treatment in major depressive disorder ( 22041458)
Interacting Genes		8 interacting genes: APP CFTR IKBKG LTA NTAQ1 SDCBP SDCBP2 TUBA4A
Entrez ID		3957
HPRD ID		08859
Ensembl ID		ENSG00000100079
Uniprot IDs		P05162
PDB IDs		1HLC 5DG1 5DG2 5EWS
Enriched GO Terms of Interacting Partners?		Protein Heterodimerization Activity Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Enzyme Binding Regulation Of Response To Calcium Ion Positive Regulation Of Cell Communication Regulation Of Type II Interferon Production Amylin Binding Positive Regulation Of JNK Cascade Positive Regulation Of Signaling Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Response To Bacterium Defense Response To Gram-positive Bacterium Regulation Of Receptor-mediated Endocytosis Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Type II Interferon Production Positive Regulation Of Intracellular Signal Transduction Cellular Response To CAMP Defense Response To Bacterium Lipoprotein Particle Regulation Of Receptor Internalization Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Import Frizzled Binding Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Positive Regulation Of Exocytosis Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Interleukin-5 Receptor Binding Interleukin-5 Receptor Complex Phosphatidylinositol-4,5-bisphosphate Binding Linear Polyubiquitin Binding Protein-N-terminal Asparagine Amidohydrolase Activity
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