LGALS2 and SDCBP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		LGALS2	SDCBP2
Description		galectin 2	syndecan binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Galectin Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Nuclear Speck Extracellular Exosome
	Molecular Function	Protein Binding Galactoside Binding Carbohydrate Binding	Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Lipid Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	T Cell Homeostasis Positive Regulation Of Apoptotic Process Positive Regulation Of Inflammatory Response Cell-cell Adhesion	Nervous System Development Cell Population Proliferation Intracellular Signal Transduction Intracellular Transport
Pathways
Drugs		Beta-D-Glucose
Diseases
GWAS		Blood protein levels ( 30072576) Response to anti-depressant treatment in major depressive disorder ( 22041458)	Estimated glomerular filtration rate ( 31152163) Metabolite levels ( 23823483)
Interacting Genes		8 interacting genes: APP CFTR IKBKG LTA NTAQ1 SDCBP SDCBP2 TUBA4A	66 interacting genes: ADAP1 AKAP17A AP1M1 ARF4 BEND7 C1orf35 CHCHD1 CRCT1 CRY2 CT45A1 CT45A10 CT45A3 CT45A5 CTH DMC1 DPPA2 EIF1AD FAM133A FAM13C FAM9B FBXO28 GABRA3 HSBP1 LGALS14 LGALS2 LYAR MED4 NFASC NFU1 NKAPD1 NOP56 NPM2 NRXN1 NUF2 PAFAH1B3 PDCD6IP PHC1 PRM2 PRPF38A PRPF40A PRR13 PTMS RNF111 RNPS1 RPL22 RPL22L1 RPL41 SDCBP SEC23A SREK1IP1 SYT17 TCP11L1 TDO2 THAP6 TIFA TM4SF1 TNNT1 TNP1 TRAF1 VAX1 VPS25 YTHDC1 ZCCHC10 ZCCHC17 ZNF581 ZRSR2
Entrez ID		3957	27111
HPRD ID		08859	18032
Ensembl ID		ENSG00000100079	ENSG00000125775
Uniprot IDs		P05162	Q9H190
PDB IDs		1HLC 5DG1 5DG2 5EWS
Enriched GO Terms of Interacting Partners?		Protein Heterodimerization Activity Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Enzyme Binding Regulation Of Response To Calcium Ion Positive Regulation Of Cell Communication Regulation Of Type II Interferon Production Amylin Binding Positive Regulation Of JNK Cascade Positive Regulation Of Signaling Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Response To Bacterium Defense Response To Gram-positive Bacterium Regulation Of Receptor-mediated Endocytosis Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Type II Interferon Production Positive Regulation Of Intracellular Signal Transduction Cellular Response To CAMP Defense Response To Bacterium Lipoprotein Particle Regulation Of Receptor Internalization Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Import Frizzled Binding Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Positive Regulation Of Exocytosis Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of Chronic Inflammatory Response To Antigenic Stimulus Interleukin-5 Receptor Binding Interleukin-5 Receptor Complex Phosphatidylinositol-4,5-bisphosphate Binding Linear Polyubiquitin Binding Protein-N-terminal Asparagine Amidohydrolase Activity	Protein Binding
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