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PRPS1

Gene Name phosphoribosyl pyrophosphate synthetase 1
Image
Gene Ontology Annotations Cellular Component
  • Cytosol
Molecular Function
  • Magnesium Ion Binding
  • Ribose Phosphate Diphosphokinase Activity
  • ATP Binding
  • Kinase Activity
  • Protein Homodimerization Activity
Biological Process
  • Carbohydrate Metabolic Process
  • 5-phosphoribose 1-diphosphate Biosynthetic Process
  • Purine Nucleobase Metabolic Process
  • Purine Nucleotide Biosynthetic Process
  • Pyrimidine Nucleotide Biosynthetic Process
  • Nervous System Development
  • Ribonucleoside Monophosphate Biosynthetic Process
  • Pathogenesis
  • Phosphorylation
  • Urate Biosynthetic Process
  • Small Molecule Metabolic Process
  • Hypoxanthine Biosynthetic Process
Pathways
  • 5-Phosphoribose 1-diphosphate biosynthesis
  • Myoclonic epilepsy of Lafora
  • Glycogen storage diseases
  • Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-protein Interactions 5 interactors: GORASP2 PRPS2 PRPSAP1 SPG21 SUMO4
Entrez ID 5631
HPRD ID 02413
Ensembl ID ENSG00000147224
Uniprot IDs B7ZB02 P60891
PDB IDs 2H06 2H07 2H08 2HCR 3EFH 3S5J 4F8E
Enriched GO Terms of Interacting Partners?
  • 5-phosphoribose 1-diphosphate Biosynthetic Process
  • AMP Biosynthetic Process
  • Nucleotide Biosynthetic Process
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