ZKSCAN4 and LXN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		ZKSCAN4	LXN
Description		zinc finger with KRAB and SCAN domains 4	latexin
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Extracellular Space Cytoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding	Enzyme Inhibitor Activity Protein Binding Metalloendopeptidase Inhibitor Activity Heparin Binding Peptidase Inhibitor Activity
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II	Inflammatory Response Detection Of Temperature Stimulus Involved In Sensory Perception Of Pain
Pathways		Generic Transcription Pathway
Drugs
Diseases
GWAS		Asthma and major depressive disorder ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Basal metabolic rate ( 31453325) Basal metabolic rate variance ( 31453325) Brain morphology (MOSTest) ( 32665545) Fish- and plant-related diet ( 32066663) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278) Schizophrenia ( 30285260) Subcortical volume (MOSTest) ( 32665545)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143)
Interacting Genes		19 interacting genes: CABP5 IL36RN LXN MAP1LC3A MDM4 MEOX2 OGT OSGIN1 PSMA6 TIAM1 TRIM39 ZKSCAN7 ZNF397 ZNF483 ZNF496 ZSCAN20 ZSCAN22 ZSCAN30 ZSCAN32	25 interacting genes: BOC CA3 COX6A1 CYBC1 DNAJC11 DPYD FCGR3A GSG1L IGSF11 MAGEA8 MCMDC2 NSMF PAX6 PPP1R3C RNF4 SHKBP1 SPAG7 TMEM14A TRAIP TRIM39 YIF1B ZCCHC17 ZKSCAN4 ZNF430 ZNF679
Entrez ID		387032	56925
HPRD ID		15768	14327
Ensembl ID		ENSG00000187626	ENSG00000079257
Uniprot IDs		A0A0S2Z658 B7Z7H3 Q969J2	Q9BS40
PDB IDs			2BO9
Enriched GO Terms of Interacting Partners?		RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Zinc Ion Binding Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Protein Catabolic Process Metal Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Purine Ribonucleoside Triphosphate Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Primary Metabolic Process Mitophagy Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process
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