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CDK5R1 and CHN1
Number of citations of the paper that reports this interaction (PMID
15013773
)
1
Data Source:
HPRD
(two hybrid, in vivo, in vitro)
CDK5R1
CHN1
Gene Name
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chimerin 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Postsynaptic Density
Membrane
Cyclin-dependent Protein Kinase 5 Holoenzyme Complex
Axon
Dendrite
Growth Cone
Neuromuscular Junction
Neuronal Cell Body
Dendritic Spine
Intracellular Membrane-bounded Organelle
Contractile Fiber
Perinuclear Region Of Cytoplasm
Cytosol
Molecular Function
Protein Kinase Activity
Cyclin-dependent Protein Serine/threonine Kinase Activity
Calcium Ion Binding
Protein Binding
Kinase Activity
Cyclin-dependent Protein Kinase 5 Activator Activity
Protein Kinase Binding
Protein Serine/threonine Kinase Activator Activity
Cadherin Binding
Ephrin Receptor Binding
SH3/SH2 Adaptor Activity
GTPase Activator Activity
Metal Ion Binding
Ephrin Receptor Binding
Biological Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Neuron Migration
Neuron Cell-cell Adhesion
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Axon Guidance
Axonal Fasciculation
Brain Development
Cell Proliferation
Embryo Development
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Cerebellum Development
Superior Olivary Nucleus Maturation
Hippocampus Development
Layer Formation In Cerebral Cortex
Neuron Differentiation
Negative Regulation Of Axon Extension
Neuron Projection Development
Regulation Of Actin Cytoskeleton Organization
Serine Phosphorylation Of STAT3 Protein
Ionotropic Glutamate Receptor Signaling Pathway
Positive Regulation Of Neuron Apoptotic Process
Regulation Of Neuron Differentiation
Negative Regulation Of Transcription, DNA-templated
Ephrin Receptor Signaling Pathway
Rhythmic Process
Regulation Of Dendritic Spine Morphogenesis
Regulation Of Microtubule Cytoskeleton Organization
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Protein Serine/threonine Kinase Activity
Positive Regulation Of Protein Targeting To Membrane
Small GTPase Mediated Signal Transduction
Motor Neuron Axon Guidance
Positive Regulation Of Signal Transduction
Regulation Of Rac GTPase Activity
Positive Regulation Of GTPase Activity
Ephrin Receptor Signaling Pathway
Regulation Of Axonogenesis
Regulation Of Small GTPase Mediated Signal Transduction
Pathways
Axon guidance
Semaphorin interactions
CRMPs in Sema3A signaling
Rho GTPase cycle
Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-Protein Interactions
31 interactors:
ACTN1
AMPH
APP
BLOC1S6
CAMK2A
CAPN1
CAPN2
CDK16
CDK5
CDK5RAP1
CDK5RAP2
CDK5RAP3
CDK9
CHN1
CTNNB1
HSP90AA1
KRT40
KRTAP10-3
LMTK2
MAPT
MTUS2
NEDD4
NES
NOTCH2NL
ODF1
PAK1
SET
SIAH1
STXBP1
TSC22D4
TTBK1
12 interactors:
ACVR1
BMPR1B
CDK5
CDK5R1
ERBB2
GTF3C1
HEMK1
MAPK8IP2
NCK2
RAC1
RPS3A
TGFBR1
Entrez ID
8851
1123
HPRD ID
04586
00319
Ensembl ID
ENSG00000176749
ENSG00000128656
Uniprot IDs
Q15078
Q8N619
P15882
PDB IDs
1H4L
1UNG
1UNH
1UNL
3O0G
2OSA
3CXL
Enriched GO Terms of Interacting Partners
?
Generation Of Neurons
Nervous System Development
Neurogenesis
Establishment Of Localization In Cell
Neuron Projection Development
Cellular Localization
Neuron Differentiation
Cell Differentiation
Cell Projection Organization
Neuron Development
Multicellular Organismal Development
Vesicle-mediated Transport
Regulation Of Organelle Organization
Regulation Of Neurogenesis
Establishment Of Organelle Localization
Regulation Of Cellular Component Organization
Developmental Process
Cell Morphogenesis Involved In Differentiation
Exocytosis
Axonogenesis
Synaptic Vesicle Transport
Regulation Of Neuron Differentiation
Cell Morphogenesis
Axon Development
Cell Morphogenesis Involved In Neuron Differentiation
Cell Projection Morphogenesis
Cell Development
Regulation Of Cell Development
System Development
Cell Part Morphogenesis
Organelle Localization
Neuron Projection Morphogenesis
Receptor Catabolic Process
Anatomical Structure Development
Synapse Organization
Regulation Of Cytoskeleton Organization
Secretion By Cell
Brain Development
Receptor Metabolic Process
Response To Abiotic Stimulus
Head Development
Establishment Of Vesicle Localization
Negative Regulation Of Neuron Death
Vesicle Localization
Axon Guidance
Regulation Of Cell Differentiation
Secretion
Anatomical Structure Morphogenesis
Regulation Of Cell Cycle
Locomotion
Cell Morphogenesis Involved In Differentiation
Cell Morphogenesis Involved In Neuron Differentiation
Cell Morphogenesis
Peptidyl-threonine Phosphorylation
Regulation Of Protein Phosphorylation
Neuron Projection Morphogenesis
Neuron Differentiation
Axon Guidance
Positive Regulation Of Protein Phosphorylation
Cell Development
Locomotion
Regulation Of Kinase Activity
Regulation Of Phosphorylation
Neuron Projection Development
Cell Projection Morphogenesis
Positive Regulation Of Phosphorylation
Cell Part Morphogenesis
Positive Regulation Of Kinase Activity
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Protein Modification Process
Regulation Of Phosphorus Metabolic Process
Movement Of Cell Or Subcellular Component
Axonogenesis
Neuron Development
Generation Of Neurons
Positive Regulation Of Transferase Activity
Signal Transduction By Phosphorylation
Axon Development
Cell Differentiation
Anatomical Structure Morphogenesis
Chemotaxis
Neurogenesis
Positive Regulation Of Cellular Protein Metabolic Process
Cell Projection Organization
Positive Regulation Of Protein Metabolic Process
Regulation Of Signal Transduction
Regulation Of Protein Kinase Activity
Positive Regulation Of Signal Transduction
Regulation Of Cellular Protein Metabolic Process
Cell Migration
Regulation Of Signaling
Regulation Of Protein Metabolic Process
Regulation Of Apoptotic Process
Positive Regulation Of Protein Kinase Activity
Serine Phosphorylation Of STAT3 Protein
Cell Motility
Nervous System Development
Regulation Of Cell Death
Serine Phosphorylation Of STAT Protein
Regulation Of Cell Differentiation
Tagcloud
?
10a
200c
30a
30c
arhgap5
cd36
cdh2
chips
cyp27b1
figure
gemcitabine
gna13
gp5
hist1h2bf
hlf
igsf3
ikbkb
il32
intriguing
mirs
nrp2
oxidoreductase
pak7
putatively
rab23
rap2a
slc11a1
sod3
tp53i3
Tagcloud (Difference)
?
10a
200c
30a
30c
arhgap5
cd36
cdh2
chips
cyp27b1
figure
gemcitabine
gna13
gp5
hist1h2bf
hlf
igsf3
ikbkb
il32
intriguing
mirs
nrp2
oxidoreductase
pak7
putatively
rab23
rap2a
slc11a1
sod3
tp53i3
Tagcloud (Intersection)
?