KRTAP10-6 and LCE4A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP10-6	LCE4A
Description		keratin associated protein 10-6	late cornified envelope 4A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding
	Biological Process		Epidermis Development Keratinization
Pathways		Keratinization	Formation of the cornified envelope
Drugs
Diseases
GWAS			Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011)
Interacting Genes		87 interacting genes: ADAMTSL3 AVPI1 CLK1 CLK4 DHX57 DKK2 FOXD4 HAND1 HHEX HOXB5 KIAA0040 KIF9 KRTAP10-1 KRTAP10-5 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MOBP MT1B NAA10 NAXD NKD1 NMU NOL12 NPDC1 PBXIP1 PIN1 RSPO2 SLC33A2 SNIP1 SPATA3 STRA6 VASN WT1 YTHDC1 ZBTB24 ZC3HAV1 ZIM2 ZNF114 ZNF138 ZNF155 ZNF169 ZNF221 ZNF239 ZNF264 ZNF280C ZNF302 ZNF319 ZNF418 ZNF440 ZNF479 ZNF490 ZNF543 ZNF563 ZNF595 ZNF600 ZNF669 ZNF672 ZNF679 ZNF696 ZNF774 ZNF776 ZNF792 ZNHIT1	79 interacting genes: ADAMTSL4 ALPP CRCT1 CREB5 CYSRT1 FUCA2 GRN HOXA1 HSD3B7 KRT31 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-1 KRTAP10-11 KRTAP10-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP17-1 KRTAP3-1 KRTAP3-2 KRTAP3-3 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE5A MDFI MEOX2 NBPF19 NOTCH2NLA NUFIP2 OTX1 P4HB PLSCR1 PLSCR3 RGS17 RGS19 RGS20 RNF111 SLC39A7 SMCP SPRY1 SPRY2 TGM1 TRIM42 TSPAN4 VASN VWC2 ZNF655
Entrez ID		386674	199834
HPRD ID		11192	17264
Ensembl ID		ENSG00000188155	ENSG00000187170
Uniprot IDs		P60371	Q5TA78
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Tissue Development Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Keratin Filament Hair Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Wnt Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Diaphragm Development Cartilage Morphogenesis Regulation Of Macromolecule Metabolic Process	Intermediate Filament Keratin Filament Epidermis Development Keratinization Tissue Development Hair Cycle Protein Binding Cytosol Lead Ion Binding Identical Protein Binding Mercury Ion Binding Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Lens Fiber Cell Differentiation Bud Elongation Involved In Lung Branching Interstitial Matrix Regulation Of Lens Fiber Cell Differentiation
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