KRTAP10-6 and NKD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP10-6	NKD1
Description		keratin associated protein 10-6	NKD inhibitor of Wnt signaling pathway 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament Keratin Filament	Protein Phosphatase Type 2A Complex Cytoplasm Plasma Membrane Membrane
	Molecular Function	Protein Binding	Calcium Ion Binding Protein Binding PDZ Domain Binding Metal Ion Binding
	Biological Process		Eye Photoreceptor Cell Differentiation Axis Elongation Somatic Muscle Development Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Positive Regulation Of MAPK Cascade Positive Regulation Of Protein Catabolic Process Convergent Extension Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Migration Involved In Somitogenic Axis Elongation Positive Regulation Of Non-canonical Wnt Signaling Pathway Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway
Pathways		Keratinization
Drugs
Diseases
GWAS			Copper levels ( 26025379) Crohn's disease ( 22412388 28067908) Inflammatory bowel disease ( 28067908) Systolic blood pressure ( 30224653)
Interacting Genes		87 interacting genes: ADAMTSL3 AVPI1 CLK1 CLK4 DHX57 DKK2 FOXD4 HAND1 HHEX HOXB5 KIAA0040 KIF9 KRTAP10-1 KRTAP10-5 KRTAP4-11 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP5-11 KRTAP5-2 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3B LCE3C LCE3D LCE3E LCE4A LCE5A MOBP MT1B NAA10 NAXD NKD1 NMU NOL12 NPDC1 PBXIP1 PIN1 RSPO2 SLC33A2 SNIP1 SPATA3 STRA6 VASN WT1 YTHDC1 ZBTB24 ZC3HAV1 ZIM2 ZNF114 ZNF138 ZNF155 ZNF169 ZNF221 ZNF239 ZNF264 ZNF280C ZNF302 ZNF319 ZNF418 ZNF440 ZNF479 ZNF490 ZNF543 ZNF563 ZNF595 ZNF600 ZNF669 ZNF672 ZNF679 ZNF696 ZNF774 ZNF776 ZNF792 ZNHIT1	15 interacting genes: AKT1 CYSRT1 DVL3 KRTAP10-1 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-9 KRTAP9-8 MDFI MORF4L1
Entrez ID		386674	85407
HPRD ID		11192	08482
Ensembl ID		ENSG00000188155	ENSG00000140807
Uniprot IDs		P60371	Q969G9
PDB IDs
Enriched GO Terms of Interacting Partners?		Keratinization Epidermis Development DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Intermediate Filament Tissue Development Zinc Ion Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding Regulation Of Transcription By RNA Polymerase II Keratin Filament Hair Cycle Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Protein Binding Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Positive Regulation Of Wnt Signaling Pathway Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Metal Ion Binding Diaphragm Development Cartilage Morphogenesis Regulation Of Macromolecule Metabolic Process	Intermediate Filament Keratin Filament Cytosol
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