EXOC8 and RAB3IL1

Number of citations of the paper that reports this interaction (PMID 19060904)
157

Data Source:
BioGRID (two hybrid)

		EXOC8	RAB3IL1
Gene Name		exocyst complex component 8	RAB3A interacting protein (rabin3)-like 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Cytoplasm Late Endosome Cytosol Plasma Membrane Membrane Growth Cone
	Molecular Function	Protein Binding Ral GTPase Binding	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity
	Biological Process	Exocyst Assembly Organelle Organization Endosome Organization Protein Transport Extracellular Matrix Disassembly Cellular Protein Metabolic Process Exocyst Localization Membrane Organization	Protein Transport Positive Regulation Of Rab GTPase Activity
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS			Oleic acid (18:1n-9) plasma levels ( 23362303) Phospholipid levels (plasma) ( 21829377)
Protein-Protein Interactions		20 interactors: BLOC1S6 CCDC85B CEP57L1 EFHC2 EXOC2 HGS IKZF3 KRT15 KRT18 KRT19 KRT20 KRT31 LNX1 MBIP PCM1 RAB3IL1 RALA TADA2A ULK1 USHBP1	13 interactors: CCDC57 EXOC8 IP6K1 KRT40 MTUS2 NOTCH2NL NUDT18 PSMA3 RAB11A RAB3A RAB3IP SATB2 TIGD7
Entrez ID		149371	5866
HPRD ID		09943	10181
Ensembl ID		ENSG00000116903	ENSG00000167994
Uniprot IDs		Q8IYI6	Q8TBN0
PDB IDs
Enriched GO Terms of Interacting Partners?		Organelle Organization Protein Localization Post-Golgi Vesicle-mediated Transport Cytoskeleton Organization Golgi To Plasma Membrane Transport Membrane Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Microtubule Anchoring Histone H3 Acetylation Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Golgi Vesicle Transport Cellular Localization Cytoplasmic Transport Radial Glia Guided Migration Of Cerebellar Granule Cell Exocytosis Establishment Of Localization In Cell Membrane Raft Localization Protein Transport Histone Acetylation Vesicle-mediated Transport Establishment Of Protein Localization Internal Peptidyl-lysine Acetylation Regulation Of Tubulin Deacetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Intracellular Transport Maintenance Of Protein Location In Cell Intraciliary Transport Involved In Cilium Morphogenesis Secretion Of Lysosomal Enzymes Microtubule-based Transport Protein Acetylation Maintenance Of Protein Location Regulation Of Cell Differentiation Cytoskeleton-dependent Intracellular Transport Maintenance Of Location In Cell Organelle Assembly Negative Regulation Of Collateral Sprouting	Endosome Organization Regulation Of Neuronal Synaptic Plasticity Rab Protein Signal Transduction Exocytosis Vesicle Docking Involved In Exocytosis Maintenance Of Presynaptic Active Zone Structure Multivesicular Body Assembly GDP Catabolic Process Regulation Of Multivesicular Body Size DGDP Catabolic Process DADP Catabolic Process Exocyst Assembly Vesicle Docking Membrane Docking Secretion By Cell Multivesicular Body Organization Cellular Protein Localization Constitutive Secretory Pathway Regulation Of Synaptic Vesicle Fusion To Presynaptic Membrane Regulation Of Endosome Size Sensory Perception Of Touch Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Secretion Exosomal Secretion Regulation Of Synaptic Plasticity Exocyst Localization Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process Establishment Of Vesicle Localization Vesicle Localization Ribonucleoside Diphosphate Catabolic Process Plasma Membrane To Endosome Transport Astral Microtubule Organization Ras Protein Signal Transduction Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Nucleoside Diphosphate Catabolic Process Organelle Organization Regulation Of Cell Cycle Phase Transition Membrane Organization Establishment Of Protein Localization To Membrane Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Protein Localization Intracellular Protein Transport Deoxyribonucleoside Diphosphate Metabolic Process Regulation Of Short-term Neuronal Synaptic Plasticity Establishment Of Localization In Cell Synaptic Vesicle Maturation
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