EXOC8 and TADA2A

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EXOC8	TADA2A
Gene Name		exocyst complex component 8	transcriptional adaptor 2A
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Exocyst Cytoplasm Late Endosome Cytosol Plasma Membrane Membrane Growth Cone	PCAF Complex Nucleus Chromosome
	Molecular Function	Protein Binding Ral GTPase Binding	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Histone Acetyltransferase Activity Zinc Ion Binding
	Biological Process	Exocyst Assembly Organelle Organization Endosome Organization Protein Transport Extracellular Matrix Disassembly Cellular Protein Metabolic Process Exocyst Localization Membrane Organization	Chromatin Organization Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Histone H3 Acetylation
Pathways		Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing	Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS			Ovarian cancer ( 23535730)
Protein-Protein Interactions		20 interactors: BLOC1S6 CCDC85B CEP57L1 EFHC2 EXOC2 HGS IKZF3 KRT15 KRT18 KRT19 KRT20 KRT31 LNX1 MBIP PCM1 RAB3IL1 RALA TADA2A ULK1 USHBP1	34 interactors: ARNT2 C1orf109 CCHCR1 CDCA7L EIF4E2 EXOC8 FAM107A FAM127C FARS2 FBF1 GPSM3 HGS KAT2A KLC4 KLHL38 KPNA2 LOC149950 MAGOH MCPH1 MFAP1 MTX2 MYC NR3C1 PPP1R16B PRKAB2 PRPF31 SF3A3 TADA3 TCF3 TEKT4 TTC23 TTC9C ZFYVE26 ZNF564
Entrez ID		149371	6871
HPRD ID		09943	03784
Ensembl ID		ENSG00000116903	ENSG00000108264
Uniprot IDs		Q8IYI6	O75478
PDB IDs			1X41
Enriched GO Terms of Interacting Partners?		Organelle Organization Protein Localization Post-Golgi Vesicle-mediated Transport Cytoskeleton Organization Golgi To Plasma Membrane Transport Membrane Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Microtubule Anchoring Histone H3 Acetylation Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Golgi To Plasma Membrane CFTR Protein Transport Golgi Vesicle Transport Cellular Localization Cytoplasmic Transport Radial Glia Guided Migration Of Cerebellar Granule Cell Exocytosis Establishment Of Localization In Cell Membrane Raft Localization Protein Transport Histone Acetylation Vesicle-mediated Transport Establishment Of Protein Localization Internal Peptidyl-lysine Acetylation Regulation Of Tubulin Deacetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Intracellular Transport Maintenance Of Protein Location In Cell Intraciliary Transport Involved In Cilium Morphogenesis Secretion Of Lysosomal Enzymes Microtubule-based Transport Protein Acetylation Maintenance Of Protein Location Regulation Of Cell Differentiation Cytoskeleton-dependent Intracellular Transport Maintenance Of Location In Cell Organelle Assembly Negative Regulation Of Collateral Sprouting	Histone H3 Acetylation Gene Expression RNA Metabolic Process Posttranscriptional Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Histone Acetylation Heterocycle Metabolic Process Internal Peptidyl-lysine Acetylation Cellular Aromatic Compound Metabolic Process Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Protein Stability Cellular Nitrogen Compound Metabolic Process Chromatin Modification Transcription, DNA-templated Cytoplasmic Transport RNA Biosynthetic Process Chromatin Organization Regulation Of Gluconeogenesis Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Glucocorticoid Mediated Signaling Pathway Exocyst Assembly Cellular Macromolecule Biosynthetic Process Establishment Of Localization In Cell Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Histone H4 Acetylation Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Organelle Organization Positive Regulation Of Cell Proliferation MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Negative Regulation Of Peptidyl-serine Dephosphorylation Fibroblast Apoptotic Process Protein Localization To Organelle Transcription From RNA Polymerase II Promoter Peptidyl-lysine Modification Intracellular Steroid Hormone Receptor Signaling Pathway Nucleocytoplasmic Transport Nuclear Transport Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Glucocorticoid Mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Regulation Of Chromosome Condensation Regulation Of Metabolic Process Cellular Protein Localization Cellular Localization
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