EXOC8 and ZNF35

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EXOC8	ZNF35
Description		exocyst complex component 8	zinc finger protein 35
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Late Endosome Cytosol Plasma Membrane Membrane Growth Cone Cell Projection Perinuclear Region Of Cytoplasm Cell Periphery	Nucleus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Small GTPase Binding Phosphatidylinositol Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Mitotic Cytokinesis Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Endosome Organization Intracellular Protein Localization Protein Transport Regulation Of Macroautophagy Extracellular Matrix Disassembly Membrane Fission Vesicle Tethering Involved In Exocytosis	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Spermatogenesis Cellular Response To Retinoic Acid
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Hemoglobin concentration ( 27863252)	Bipolar disorder ( 31043756)
Interacting Genes		88 interacting genes: AIMP2 ANKRD36B ATP23 BEX2 BICRAL BLOC1S2 BLOC1S6 BLZF1 BORCS6 CAPN3 CCDC33 CCDC85B CCHCR1 CDSN CEP57L1 CWF19L2 DMAP1 EFHC2 ELL2 ESS2 EXOC2 FAM217B GOLGA2 GRAMD4 GTF2E2 HGS IHO1 IKZF3 ISY1 ISY1-RAB43 KIAA1217 KIFC3 KRT15 KRT18 KRT19 KRT20 KRT31 KRT34 KRT36 KRT76 LNX1 LZTS1 MARCHF7 MBD3L1 MBIP MIPOL1 MTUS2 MYOZ3 NAB2 NDC80 NUP54 PBX4 PCM1 PRR35 RAB3IL1 RALA RAPGEF3 RINT1 RUSC1 SASH1 SCARA5 SNAPC1 STMN3 SYCE1 SYT17 TADA2A TBC1D22B TCF12 TCF4 TFIP11 TRIM14 TRIM21 TRIM27 TRIM54 ULK1 UQCC2 USHBP1 USP54 VPS16 VPS37B WASHC1 ZC2HC1A ZNF177 ZNF35 ZNF559-ZNF177 ZNF566 ZNF628 ZSCAN4	32 interacting genes: APP ATPAF2 CCDC136 CDC5L CDR2 CDR2L CEP70 CREB1 CWF19L2 EEF2KMT EXOC8 FSD2 GEMIN4 GOLGA2 GOLGA6L9 GRIPAP1 HOMER3 HOMEZ HOOK1 HOOK2 LZTS1 MCC MTUS2 MYD88 NDEL1 PIBF1 PICK1 PNMA1 PRKAR1B TRAF2 YJU2B ZBTB8A
Entrez ID		149371	7584
HPRD ID		09943	01920
Ensembl ID		ENSG00000116903	ENSG00000169981
Uniprot IDs		Q8IYI6	P13682
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Protein Binding Supramolecular Fiber Organization Intermediate Filament Organelle Organization Structural Molecule Activity Negative Regulation Of Viral Transcription Cytoskeleton Regulation Of Viral Transcription Regulation Of Post-translational Protein Modification Regulation Of Protein Autoubiquitination Molecular Adaptor Activity Cytoskeleton Organization Identical Protein Binding Phosphatidylinositol 3-kinase Inhibitor Activity Cellular Localization Vesicle-mediated Transport To The Plasma Membrane Regulation Of Lysosome Size BORC Complex Post-mRNA Release Spliceosomal Complex Gamma-tubulin Binding Autophagosome Epidermis Development	Identical Protein Binding Positive Regulation Of Long-term Synaptic Potentiation Cytoskeleton-dependent Intracellular Transport Regulation Of Synaptic Plasticity FHF Complex Regulation Of Long-term Synaptic Potentiation Microtubule Binding Protein Localization To Perinuclear Region Of Cytoplasm Post-mRNA Release Spliceosomal Complex Centrosome Modulation Of Chemical Synaptic Transmission Vesicle Organization HOPS Complex Microtubule Protein Binding Endosome Organization Microtubule-based Process
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