P2RX4

Gene Name		purinergic receptor P2X, ligand gated ion channel, 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Nuclear Inner Membrane Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Postsynaptic Density Membrane Cell Junction Neuronal Cell Body Terminal Bouton Dendritic Spine Apical Part Of Cell Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Purinergic Nucleotide Receptor Activity Extracellular ATP-gated Cation Channel Activity Receptor Binding Copper Ion Binding ATP Binding Drug Binding Zinc Ion Binding Protein Homodimerization Activity Cadherin Binding
	Biological Process	Tissue Homeostasis Regulation Of Sodium Ion Transport Nitric Oxide Biosynthetic Process Transport Calcium Ion Transport Signal Transduction Regulation Of Blood Pressure Positive Regulation Of Calcium Ion Transport Into Cytosol Negative Regulation Of Cardiac Muscle Hypertrophy Neuronal Action Potential Sensory Perception Of Pain Positive Regulation Of Prostaglandin Secretion Response To ATP Ion Transmembrane Transport Response To Fluid Shear Stress Purinergic Nucleotide Receptor Signaling Pathway Endothelial Cell Activation Vasodilation Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Calcium-mediated Signaling Protein Homooligomerization Membrane Depolarization Positive Regulation Of Calcium Ion Transport Regulation Of Cardiac Muscle Contraction Relaxation Of Cardiac Muscle Regulation Of Excitatory Postsynaptic Membrane Potential Cellular Response To ATP Apoptotic Signaling Pathway Cation Transmembrane Transport
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: CDH5 KRTAP5-9 MCM2 NOTCH2NL PIH1D3 WNT4
Entrez ID		5025
HPRD ID		09017
Ensembl ID		ENSG00000135124
Uniprot IDs		E7EPF7 F6RU17 Q5U089 Q99571
PDB IDs
Enriched GO Terms of Interacting Partners?		Immature T Cell Proliferation In Thymus Positive Regulation Of Cortisol Biosynthetic Process Negative Regulation Of Testicular Blood Vessel Morphogenesis Negative Regulation Of Testosterone Biosynthetic Process Negative Regulation Of Male Gonad Development Positive Regulation Of Aldosterone Biosynthetic Process Female Sex Determination Regulation Of Testosterone Biosynthetic Process Tertiary Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Dermatome Development Thyroid-stimulating Hormone-secreting Cell Differentiation Renal Vesicle Induction Paramesonephric Duct Development Somatotropin Secreting Cell Differentiation Metanephric Mesenchymal Cell Differentiation Metanephric Tubule Formation Non-canonical Wnt Signaling Pathway Via MAPK Cascade Neuroendocrine Cell Differentiation Positive Regulation Of Steroid Hormone Biosynthetic Process Mesenchymal Cell Differentiation Involved In Kidney Development Mammary Gland Branching Involved In Pregnancy Renal Vesicle Formation Blood Vessel Maturation Regulation Of Glucocorticoid Biosynthetic Process Negative Regulation Of Hormone Biosynthetic Process DNA Unwinding Involved In DNA Replication Positive Regulation Of Hormone Biosynthetic Process Regulation Of Glucocorticoid Metabolic Process Cell Differentiation Involved In Metanephros Development Metanephric Tubule Morphogenesis Adenohypophysis Development Axonemal Dynein Complex Assembly Renal Vesicle Morphogenesis Androgen Biosynthetic Process Mesenchymal To Epithelial Transition Positive Regulation Of Meiotic Nuclear Division Metanephric Mesenchyme Development Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Steroid Metabolic Process Metanephric Nephron Morphogenesis Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Cellular Response To Epidermal Growth Factor Stimulus Sex Determination Regulation Of Hormone Biosynthetic Process Positive Regulation Of Collagen Biosynthetic Process Positive Regulation Of Steroid Metabolic Process Positive Regulation Of Collagen Metabolic Process DNA Strand Elongation Involved In DNA Replication
Tagcloud ?		acaa1 analogous ap1m2 aspirates cgn combat dcn ddr1 deadly ec ecs efemp2 endometrial eps8l2 fastkd1 gmip ikbke minimally noncarcinoma p4hb phkg2 ppfibp2 ppp1r16a rassf7 rnf183 sirt6 socs2 tjp3 uterine